001     178293
005     20240229133803.0
024 7 _ |a 10.17116/neiro20218506198
|2 doi
024 7 _ |a pmid:34951766
|2 pmid
037 _ _ |a DKFZ-2021-03240
041 _ _ |a Russian
082 _ _ |a 610
100 1 _ |a Ryzhova, M. V.
|b 0
245 _ _ |a Sovremennye diagnosticheskie vozmozhnosti molekulyarnogo issledovaniya opukholei mozga v Tsentre neirokhirurgii im. akad. N.N. Burdenko.
260 _ _ |a Moskva
|c 2021
|b Nakl. Medicina
336 7 _ |a article
|2 DRIVER
336 7 _ |a Output Types/Journal article
|2 DataCite
336 7 _ |a Journal Article
|b journal
|m journal
|0 PUB:(DE-HGF)16
|s 1641068520_10897
|2 PUB:(DE-HGF)
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a Journal Article
|0 0
|2 EndNote
500 _ _ |a #LA:B062#
520 _ _ |a DnA methylation has recently been accepted as the most reliable and effective method of diagnosing central nervous system (CNS) tumors. Healthy organs and tumors of different localizations have their own unique methylation structure. Determination of total tumor DNA methylome is the detection of all methylated nucleotides in a tumor. The 'gold standard' for analyzing the methylation state of individual cytosines is bisulfite conversion, in which unmethylated cytosines are converted to uracils and read as thymines, while methylated cytosines are protected from conversion.
536 _ _ |a 312 - Funktionelle und strukturelle Genomforschung (POF4-312)
|0 G:(DE-HGF)POF4-312
|c POF4-312
|f POF IV
|x 0
588 _ _ |a Dataset connected to CrossRef, PubMed, , Journals: inrepo01.inet.dkfz-heidelberg.de
650 _ 7 |a DNA methylation
|2 Other
650 _ 7 |a EPIC array
|2 Other
650 _ 7 |a Illumina Infinium HumanMethylation850 BeadChip
|2 Other
650 _ 7 |a DNA
|0 9007-49-2
|2 NLM Chemicals
650 _ 2 |a Brain Neoplasms: genetics
|2 MeSH
650 _ 2 |a DNA: metabolism
|2 MeSH
650 _ 2 |a DNA Methylation
|2 MeSH
650 _ 2 |a Humans
|2 MeSH
700 1 _ |a Telysheva, E. N.
|b 1
700 1 _ |a Shaikhaev, E. G.
|0 0000-0002-7882-2579
|b 2
700 1 _ |a Starovoitov, D. V.
|0 0000-0002-1879-393X
|b 3
700 1 _ |a Kotelnikova, A. O.
|b 4
700 1 _ |a Galstyan, S. A.
|0 0000-0001-9953-6654
|b 5
700 1 _ |a Okonechnikov, Konstantin
|0 P:(DE-He78)34b3639de467b2c700920d7cbc3d2110
|b 6
|e Last author
|u dkfz
773 _ _ |a 10.17116/neiro20218506198
|g Vol. 85, no. 6, p. 98 -
|0 PERI:(DE-600)603458-5
|n 6
|p 98
|t Zurnal voprosy nejrochirurgii imeni N.N. Burdenko
|v 85
|y 2021
|x 0042-8817
909 C O |o oai:inrepo02.dkfz.de:178293
|p VDB
910 1 _ |a Deutsches Krebsforschungszentrum
|0 I:(DE-588b)2036810-0
|k DKFZ
|b 6
|6 P:(DE-He78)34b3639de467b2c700920d7cbc3d2110
913 1 _ |a DE-HGF
|b Gesundheit
|l Krebsforschung
|1 G:(DE-HGF)POF4-310
|0 G:(DE-HGF)POF4-312
|3 G:(DE-HGF)POF4
|2 G:(DE-HGF)POF4-300
|4 G:(DE-HGF)POF
|v Funktionelle und strukturelle Genomforschung
|x 0
914 1 _ |y 2021
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0200
|2 StatID
|b SCOPUS
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0300
|2 StatID
|b Medline
920 1 _ |0 I:(DE-He78)B062-20160331
|k B062
|l B062 Pädiatrische Neuroonkologie
|x 0
980 _ _ |a journal
980 _ _ |a VDB
980 _ _ |a I:(DE-He78)B062-20160331
980 _ _ |a UNRESTRICTED


LibraryCollectionCLSMajorCLSMinorLanguageAuthor
Marc 21