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000178602 041__ $$aEnglish
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000178602 1001_ $$00000-0002-3573-4501$$aPhung, Minh Tung$$b0
000178602 245__ $$aReproductive factors do not influence survival with ovarian cancer.
000178602 260__ $$aPhiladelphia, Pa.$$bAACR$$c2022
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000178602 500__ $$a 2022 Apr 1;31(4):909-913
000178602 520__ $$aBackground Previous studies on the association between reproductive factors and ovarian cancer survival are equivocal, possibly due to small sample sizes. Methods Using data on 11,175 people diagnosed with primary invasive epithelial ovarian, fallopian tube, or primary peritoneal cancer (ovarian cancer) from 16 studies in the Ovarian Cancer Association Consortium (OCAC), we examined the associations between survival and age at menarche, combined oral contraceptive use, parity, breastfeeding, age at last pregnancy, and menopausal status using Cox proportional hazard models. The models were adjusted for age at diagnosis, race/ethnicity, education level, and OCAC study and stratified on stage and histotype. Results During the mean follow-up of 6.34 years (SD=4.80), 6,418 patients passed away (57.4%). There was no evidence of associations between the reproductive factors and survival among ovarian cancer patients overall or by histotype. Conclusions This study found no association between reproductive factors and survival after an ovarian cancer diagnosis. Impact Reproductive factors are well-established risk factors for ovarian cancer, but they are not associated with survival after a diagnosis of ovarian cancer.
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000178602 7001_ $$aAlimujiang, Aliya$$b1
000178602 7001_ $$aBerchuck, Andrew$$b2
000178602 7001_ $$aAnton-Cluver, Hoda$$b3
000178602 7001_ $$aSchildkraut, Joellen M$$b4
000178602 7001_ $$00000-0002-8789-2755$$aBandera, Elisa V$$b5
000178602 7001_ $$0P:(DE-He78)c259d6cc99edf5c7bc7ce22c7f87c253$$aChang-Claude, Jenny$$b6$$udkfz
000178602 7001_ $$aChase, Anne$$b7
000178602 7001_ $$00000-0002-1454-8187$$aDoherty, Jennifer Anne$$b8
000178602 7001_ $$aGrout, Bronwyn$$b9
000178602 7001_ $$aGoodman, Marc T$$b10
000178602 7001_ $$aHanley, Gillian E$$b11
000178602 7001_ $$00000-0001-8756-7066$$aLee, Alice W$$b12
000178602 7001_ $$aMcKinnon Deurloo, Cindy$$b13
000178602 7001_ $$00000-0003-3708-1732$$aMenon, Usha$$b14
000178602 7001_ $$00000-0003-0637-1534$$aModugno, Francesmary$$b15
000178602 7001_ $$00000-0001-8494-732X$$aPharoah, Paul D P$$b16
000178602 7001_ $$00000-0003-4891-1199$$aPike, Malcolm C$$b17
000178602 7001_ $$00000-0002-8273-6518$$aRichardson, Jean$$b18
000178602 7001_ $$aRisch, Harvey A$$b19
000178602 7001_ $$00000-0003-0085-1190$$aSieh, Weiva$$b20
000178602 7001_ $$aTerry, Kathryn L$$b21
000178602 7001_ $$00000-0003-0733-5930$$aWebb, Penelope M$$b22
000178602 7001_ $$aWentzensen, Nicolas$$b23
000178602 7001_ $$aWu, Anna H$$b24
000178602 7001_ $$aPearce, Celeste Leigh$$b25
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