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@ARTICLE{Phung:178602,
author = {M. T. Phung and A. Alimujiang and A. Berchuck and H.
Anton-Cluver and J. M. Schildkraut and E. V. Bandera and J.
Chang-Claude$^*$ and A. Chase and J. A. Doherty and B. Grout
and M. T. Goodman and G. E. Hanley and A. W. Lee and C.
McKinnon Deurloo and U. Menon and F. Modugno and P. D. P.
Pharoah and M. C. Pike and J. Richardson and H. A. Risch and
W. Sieh and K. L. Terry and P. M. Webb and N. Wentzensen and
A. H. Wu and C. L. Pearce},
title = {{R}eproductive factors do not influence survival with
ovarian cancer.},
journal = {Cancer epidemiology, biomarkers $\&$ prevention},
volume = {31},
number = {4},
issn = {1055-9965},
address = {Philadelphia, Pa.},
publisher = {AACR},
reportid = {DKFZ-2022-00151},
pages = {909-913},
year = {2022},
note = {2022 Apr 1;31(4):909-913},
abstract = {Background Previous studies on the association between
reproductive factors and ovarian cancer survival are
equivocal, possibly due to small sample sizes. Methods Using
data on 11,175 people diagnosed with primary invasive
epithelial ovarian, fallopian tube, or primary peritoneal
cancer (ovarian cancer) from 16 studies in the Ovarian
Cancer Association Consortium (OCAC), we examined the
associations between survival and age at menarche, combined
oral contraceptive use, parity, breastfeeding, age at last
pregnancy, and menopausal status using Cox proportional
hazard models. The models were adjusted for age at
diagnosis, race/ethnicity, education level, and OCAC study
and stratified on stage and histotype. Results During the
mean follow-up of 6.34 years (SD=4.80), 6,418 patients
passed away $(57.4\%).$ There was no evidence of
associations between the reproductive factors and survival
among ovarian cancer patients overall or by histotype.
Conclusions This study found no association between
reproductive factors and survival after an ovarian cancer
diagnosis. Impact Reproductive factors are well-established
risk factors for ovarian cancer, but they are not associated
with survival after a diagnosis of ovarian cancer.},
cin = {C020},
ddc = {610},
cid = {I:(DE-He78)C020-20160331},
pnm = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
pid = {G:(DE-HGF)POF4-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:35064059},
doi = {10.1158/1055-9965.EPI-21-1091},
url = {https://inrepo02.dkfz.de/record/178602},
}