% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Holm:178653,
      author       = {K. M. Holm and O. Jaekel$^*$ and A. Krauss},
      title        = {{D}irect determination ofk{Q}for {F}armer-type ionization
                      chambers in a clinical scanned carbon-ion beam using water
                      calorimetry.},
      journal      = {Physics in medicine and biology},
      volume       = {67},
      number       = {4},
      issn         = {0031-9155},
      address      = {Bristol},
      publisher    = {IOP Publ.},
      reportid     = {DKFZ-2022-00182},
      pages        = {049401},
      year         = {2022},
      note         = {Phys. Med. Biol. 67 (2022) 049401},
      abstract     = {Within two studies, kQ factors for two Farmer-type
                      ionization chambers have been experimentally determined by
                      means of water calorimetry in the entrance channel (EC) of a
                      monoenergetic carbon-ion beam [1] and for a passively
                      modulated spread-out Bragg peak (SOBP) [2]. Both studies
                      were performed at the Heidelberg Ion Beam Therapy Center
                      (HIT) using the PTB portable water calorimeter but applying
                      different initial beam energies of 429 MeV/u for the EC and
                      278 MeV/u for the SOBP as well as different scanning
                      patterns of the irradiated eld. Comparing their results
                      revealed differences between the experimental kQ factors of
                      up to $1.9\%$ between the EC and the SOBP. To further
                      investigate this unexpected difference, we performed
                      additional kQ determinations for the EC of an 278 MeV/u
                      monoenergetic carbon-ion beam and reevaluated the original
                      data of Osinga-Blättermann et al. [1]. This new
                      experimental data indicated no difference between the kQ
                      factors for the EC and the SOBP and the reevaluation led to
                      a substantial reduction of the originally published kQ
                      factors for the EC of the 429 MeV/u beam [1]. Finally, no
                      signicant difference between the data for the EC and the
                      data for the SOBP can be found within the standard
                      measurement uncertainty of experimental kQ factors of 0.8
                      $\%.$ The results presented here are intended to correct and
                      replace the kQ data published by Osinga- Blättermann et al.
                      [1] and in Osinga-Blättermann and Krauss [3].},
      keywords     = {SOBP (Other) / carbon-ion beams (Other) / entrance channel
                      (Other) / kQ factors (Other) / water calorimetry (Other)},
      cin          = {E040},
      ddc          = {530},
      cid          = {I:(DE-He78)E040-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:35086066},
      doi          = {10.1088/1361-6560/ac4fa0},
      url          = {https://inrepo02.dkfz.de/record/178653},
}