Journal Article DKFZ-2022-00182

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Direct determination ofkQfor Farmer-type ionization chambers in a clinical scanned carbon-ion beam using water calorimetry.

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2022
IOP Publ. Bristol

Physics in medicine and biology 67(4), 049401 () [10.1088/1361-6560/ac4fa0]
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Abstract: Within two studies, kQ factors for two Farmer-type ionization chambers have been experimentally determined by means of water calorimetry in the entrance channel (EC) of a monoenergetic carbon-ion beam [1] and for a passively modulated spread-out Bragg peak (SOBP) [2]. Both studies were performed at the Heidelberg Ion Beam Therapy Center (HIT) using the PTB portable water calorimeter but applying different initial beam energies of 429 MeV/u for the EC and 278 MeV/u for the SOBP as well as different scanning patterns of the irradiated eld. Comparing their results revealed differences between the experimental kQ factors of up to 1.9% between the EC and the SOBP. To further investigate this unexpected difference, we performed additional kQ determinations for the EC of an 278 MeV/u monoenergetic carbon-ion beam and reevaluated the original data of Osinga-Blättermann et al. [1]. This new experimental data indicated no difference between the kQ factors for the EC and the SOBP and the reevaluation led to a substantial reduction of the originally published kQ factors for the EC of the 429 MeV/u beam [1]. Finally, no signicant difference between the data for the EC and the data for the SOBP can be found within the standard measurement uncertainty of experimental kQ factors of 0.8 %. The results presented here are intended to correct and replace the kQ data published by Osinga- Blättermann et al. [1] and in Osinga-Blättermann and Krauss [3].

Keyword(s): SOBP ; carbon-ion beams ; entrance channel ; kQ factors ; water calorimetry

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Note: Phys. Med. Biol. 67 (2022) 049401

Contributing Institute(s):
  1. E040 Med. Physik in der Strahlentherapie (E040)
Research Program(s):
  1. 315 - Bildgebung und Radioonkologie (POF4-315) (POF4-315)

Appears in the scientific report 2022
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 Record created 2022-01-28, last modified 2024-02-29



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