Journal Article

DKFZ-2022-02051

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png oChanges in Radical Levels as a Cause for the FLASH effect: Impact of beam structure parameters at ultra-high dose rates on oxygen depletion in water.

Jansen, J. (First author)DKFZ* ; Beyreuther, E. ; García-Calderón, D.DKFZ* ; Karsch, L. ; Knoll, J.DKFZ* ; Pawelke, J. ; Schürer, M. ; Seco, J. (Last author)DKFZ*

2022
Elsevier Science Amsterdam [u.a.]

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Please use a persistent id in citations: doi:10.1016/j.radonc.2022.08.024

Abstract: The influence of different average and bunch dose rates in electron beams on the FLASH effect was investigated. The present study measures O2 content in water at different beam pulse patterns and finds strong correlation with biological data, strengthening the hypothesis of radical-related mechanisms as a reason for the FLASH effect.

Keyword(s): FLASH effect ; oxygen depletion ; pulse structure ; radical reduction

Note: #EA:E041#LA:E041# / 2022 Oct;175:193-196

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Contributing Institute(s):

1. E041 Med. Physik in der Radioonkologie (E041)

Research Program(s):

1. 315 - Bildgebung und Radioonkologie (POF4-315) (POF4-315)

Appears in the scientific report 2022

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Database coverage:
; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 5 ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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