TY  - JOUR
AU  - Pham, Thu-Thi
AU  - Nimptsch, Katharina
AU  - Aleksandrova, Krasimira
AU  - Jenab, Mazda
AU  - Reichmann, Robin
AU  - Wu, Kana
AU  - Tjønneland, Anne
AU  - Kyrø, Cecilie
AU  - Schulze, Matthias B
AU  - Kaaks, Rudolf
AU  - Katzke, Verena
AU  - Palli, Domenico
AU  - Pasanisi, Fabrizio
AU  - Ricceri, Fulvio
AU  - Tumino, Rosario
AU  - Krogh, Vittorio
AU  - Roodhart, Jeanine
AU  - Castilla, Jesús
AU  - Sánchez, Maria-Jose
AU  - Colorado-Yohar, Sandra Milena
AU  - Harbs, Justin
AU  - Rutegård, Martin
AU  - Papier, Keren
AU  - Aglago, Elom K
AU  - Dimou, Niki
AU  - Mayen-Chacon, Ana-Lucia
AU  - Weiderpass, Elisabete
AU  - Pischon, Tobias
TI  - Pre-Diagnostic Circulating Resistin Concentrations Are Not Associated with Colorectal Cancer Risk in the European Prospective Investigation into Cancer and Nutrition Study.
JO  - Cancers
VL  - 14
IS  - 22
SN  - 2072-6694
CY  - Basel
PB  - MDPI
M1  - DKFZ-2022-02930
SP  - 5499
PY  - 2022
AB  - Resistin is a polypeptide implicated in inflammatory processes, and as such could be linked to colorectal carcinogenesis. In case-control studies, higher resistin levels have been found in colorectal cancer (CRC) patients compared to healthy individuals. However, evidence for the association between pre-diagnostic resistin and CRC risk is scarce. We investigated pre-diagnostic resistin concentrations and CRC risk within the European Prospective Investigation into Cancer and Nutrition using a nested case-control study among 1293 incident CRC-diagnosed cases and 1293 incidence density-matched controls. Conditional logistic regression models controlled for matching factors (age, sex, study center, fasting status, and women-related factors in women) and potential confounders (education, dietary and lifestyle factors, body mass index (BMI), BMI-adjusted waist circumference residuals) were used to estimate relative risks (RRs) and 95
KW  - colorectal cancer (Other)
KW  - inflammation (Other)
KW  - pre-diagnostic resistin (Other)
KW  - prospective (Other)
KW  - risk (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:36428592
DO  - DOI:10.3390/cancers14225499
UR  - https://inrepo02.dkfz.de/record/182798
ER  -