%0 Journal Article
%A Gil-Lespinard, Mercedes
%A Castañeda, Jazmín
%A Almanza-Aguilera, Enrique
%A Gómez, Jesús Humberto
%A Tjønneland, Anne
%A Kyrø, Cecilie
%A Overvad, Kim
%A Katzke, Verena
%A Schulze, Matthias B
%A Masala, Giovanna
%A Agnoli, Claudia
%A Santucci de Magistris, Maria
%A Tumino, Rosario
%A Sacerdote, Carlotta
%A Skeie, Guri
%A Lasheras, Cristina
%A Molina-Montes, Esther
%A Huerta, José María
%A Barricarte, Aurelio
%A Amiano, Pilar
%A Sonestedt, Emily
%A da Silva, Marisa
%A Johansson, Ingegerd
%A Hultdin, Johan
%A May, Anne M
%A Forouhi, Nita G
%A Heath, Alicia K
%A Freisling, Heinz
%A Weiderpass, Elisabete
%A Scalbert, Augustin
%A Zamora-Ros, Raul
%T Dietary Intake of 91 Individual Polyphenols and 5-Year Body Weight Change in the EPIC-PANACEA Cohort.
%J Antioxidants
%V 11
%N 12
%@ 2076-3921
%C Basel
%I MDPI
%M DKFZ-2022-03186
%P 2425
%D 2022
%X Polyphenols are bioactive compounds from plants with antioxidant properties that may have a protective role against body weight gain, with adipose tissue and systemic oxidative stress as potential targets. We aimed to investigate the dietary intake of individual polyphenols and their association with 5-year body weight change in a sub-cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC). This study included 349,165 adult participants from nine European countries. Polyphenol intake was estimated through country-specific validated dietary questionnaires and the Phenol-Explorer database. Body weight was obtained at recruitment and after a mean follow-up time of 5 years. Associations were estimated using multilevel mixed linear regression models. From 91 polyphenols included, the majority (n = 67) were inversely associated with 5-year body weight change after FDR-correction (q < 0.05). The greatest inverse associations were observed for quercetin 3-O-rhamnoside (change in weight for doubling in intake: -0.071 (95
%K EPIC (Other)
%K body weight (Other)
%K cohort (Other)
%K intake (Other)
%K obesity (Other)
%K polyphenol (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:36552633
%2 pmc:PMC9774775
%R 10.3390/antiox11122425
%U https://inrepo02.dkfz.de/record/186465