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000186465 041__ $$aEnglish
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000186465 1001_ $$aGil-Lespinard, Mercedes$$b0
000186465 245__ $$aDietary Intake of 91 Individual Polyphenols and 5-Year Body Weight Change in the EPIC-PANACEA Cohort.
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000186465 520__ $$aPolyphenols are bioactive compounds from plants with antioxidant properties that may have a protective role against body weight gain, with adipose tissue and systemic oxidative stress as potential targets. We aimed to investigate the dietary intake of individual polyphenols and their association with 5-year body weight change in a sub-cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC). This study included 349,165 adult participants from nine European countries. Polyphenol intake was estimated through country-specific validated dietary questionnaires and the Phenol-Explorer database. Body weight was obtained at recruitment and after a mean follow-up time of 5 years. Associations were estimated using multilevel mixed linear regression models. From 91 polyphenols included, the majority (n = 67) were inversely associated with 5-year body weight change after FDR-correction (q < 0.05). The greatest inverse associations were observed for quercetin 3-O-rhamnoside (change in weight for doubling in intake: -0.071 (95% CI: -0.085; -0.056) kg/5 years). Only 13 polyphenols showed positive associations with body weight gain, mainly from the subclass hydroxycinnamic acids (HCAs) with coffee as the main dietary source, such as 4-caffeoylquinic acid (0.029 (95% CI: 0.021; 0.038) kg/5 years). Individual polyphenols with fruit, tea, cocoa and whole grain cereals as the main dietary sources may contribute to body weight maintenance in adults. Individual HCAs may have different roles in body weight change depending on their dietary source.
000186465 536__ $$0G:(DE-HGF)POF4-313$$a313 - Krebsrisikofaktoren und Prävention (POF4-313)$$cPOF4-313$$fPOF IV$$x0
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000186465 650_7 $$2Other$$aEPIC
000186465 650_7 $$2Other$$abody weight
000186465 650_7 $$2Other$$acohort
000186465 650_7 $$2Other$$aintake
000186465 650_7 $$2Other$$aobesity
000186465 650_7 $$2Other$$apolyphenol
000186465 7001_ $$aCastañeda, Jazmín$$b1
000186465 7001_ $$00000-0002-4805-0774$$aAlmanza-Aguilera, Enrique$$b2
000186465 7001_ $$aGómez, Jesús Humberto$$b3
000186465 7001_ $$aTjønneland, Anne$$b4
000186465 7001_ $$00000-0002-9083-8960$$aKyrø, Cecilie$$b5
000186465 7001_ $$aOvervad, Kim$$b6
000186465 7001_ $$0P:(DE-He78)fb68a9386399d72d84f7f34cfc6048b4$$aKatzke, Verena$$b7$$udkfz
000186465 7001_ $$aSchulze, Matthias B$$b8
000186465 7001_ $$00000-0002-5758-9069$$aMasala, Giovanna$$b9
000186465 7001_ $$aAgnoli, Claudia$$b10
000186465 7001_ $$aSantucci de Magistris, Maria$$b11
000186465 7001_ $$00000-0003-2666-414X$$aTumino, Rosario$$b12
000186465 7001_ $$00000-0002-8008-5096$$aSacerdote, Carlotta$$b13
000186465 7001_ $$00000-0003-2476-4251$$aSkeie, Guri$$b14
000186465 7001_ $$aLasheras, Cristina$$b15
000186465 7001_ $$00000-0002-0428-2426$$aMolina-Montes, Esther$$b16
000186465 7001_ $$00000-0002-9637-3869$$aHuerta, José María$$b17
000186465 7001_ $$aBarricarte, Aurelio$$b18
000186465 7001_ $$aAmiano, Pilar$$b19
000186465 7001_ $$00000-0002-0747-4562$$aSonestedt, Emily$$b20
000186465 7001_ $$00000-0003-1215-8625$$ada Silva, Marisa$$b21
000186465 7001_ $$00000-0002-9227-8434$$aJohansson, Ingegerd$$b22
000186465 7001_ $$00000-0002-9599-0961$$aHultdin, Johan$$b23
000186465 7001_ $$aMay, Anne M$$b24
000186465 7001_ $$aForouhi, Nita G$$b25
000186465 7001_ $$00000-0001-6517-1300$$aHeath, Alicia K$$b26
000186465 7001_ $$00000-0001-8648-4998$$aFreisling, Heinz$$b27
000186465 7001_ $$00000-0003-2237-0128$$aWeiderpass, Elisabete$$b28
000186465 7001_ $$aScalbert, Augustin$$b29
000186465 7001_ $$00000-0002-6236-6804$$aZamora-Ros, Raul$$b30
000186465 773__ $$0PERI:(DE-600)2704216-9$$a10.3390/antiox11122425$$gVol. 11, no. 12, p. 2425 -$$n12$$p2425$$tAntioxidants$$v11$$x2076-3921$$y2022
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