TY  - JOUR
AU  - Gil-Lespinard, Mercedes
AU  - Castañeda, Jazmín
AU  - Almanza-Aguilera, Enrique
AU  - Gómez, Jesús Humberto
AU  - Tjønneland, Anne
AU  - Kyrø, Cecilie
AU  - Overvad, Kim
AU  - Katzke, Verena
AU  - Schulze, Matthias B
AU  - Masala, Giovanna
AU  - Agnoli, Claudia
AU  - Santucci de Magistris, Maria
AU  - Tumino, Rosario
AU  - Sacerdote, Carlotta
AU  - Skeie, Guri
AU  - Lasheras, Cristina
AU  - Molina-Montes, Esther
AU  - Huerta, José María
AU  - Barricarte, Aurelio
AU  - Amiano, Pilar
AU  - Sonestedt, Emily
AU  - da Silva, Marisa
AU  - Johansson, Ingegerd
AU  - Hultdin, Johan
AU  - May, Anne M
AU  - Forouhi, Nita G
AU  - Heath, Alicia K
AU  - Freisling, Heinz
AU  - Weiderpass, Elisabete
AU  - Scalbert, Augustin
AU  - Zamora-Ros, Raul
TI  - Dietary Intake of 91 Individual Polyphenols and 5-Year Body Weight Change in the EPIC-PANACEA Cohort.
JO  - Antioxidants
VL  - 11
IS  - 12
SN  - 2076-3921
CY  - Basel
PB  - MDPI
M1  - DKFZ-2022-03186
SP  - 2425
PY  - 2022
AB  - Polyphenols are bioactive compounds from plants with antioxidant properties that may have a protective role against body weight gain, with adipose tissue and systemic oxidative stress as potential targets. We aimed to investigate the dietary intake of individual polyphenols and their association with 5-year body weight change in a sub-cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC). This study included 349,165 adult participants from nine European countries. Polyphenol intake was estimated through country-specific validated dietary questionnaires and the Phenol-Explorer database. Body weight was obtained at recruitment and after a mean follow-up time of 5 years. Associations were estimated using multilevel mixed linear regression models. From 91 polyphenols included, the majority (n = 67) were inversely associated with 5-year body weight change after FDR-correction (q < 0.05). The greatest inverse associations were observed for quercetin 3-O-rhamnoside (change in weight for doubling in intake: -0.071 (95
KW  - EPIC (Other)
KW  - body weight (Other)
KW  - cohort (Other)
KW  - intake (Other)
KW  - obesity (Other)
KW  - polyphenol (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:36552633
C2  - pmc:PMC9774775
DO  - DOI:10.3390/antiox11122425
UR  - https://inrepo02.dkfz.de/record/186465
ER  -