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| Home > Publications database > Grip strength values and cut-off points based on over 200,000 adults of the German National Cohort - a comparison to the EWGSOP2 cut-off points. > print |
| 001 | 212515 | ||
| 005 | 20240229154913.0 | ||
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| 100 | 1 | _ | |a Huemer, Marie-Theres |b 0 |
| 245 | _ | _ | |a Grip strength values and cut-off points based on over 200,000 adults of the German National Cohort - a comparison to the EWGSOP2 cut-off points. |
| 260 | _ | _ | |a Oxford |c 2023 |b Oxford Univ. Press |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1675070724_31442 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
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| 520 | _ | _ | |a The European Working Group on Sarcopenia in Older People (EWGSOP) updated in 2018 the cut-off points for low grip strength to assess sarcopenia based on pooled data from 12 British studies.Comparison of the EWGSOP2 cut-off points for low grip strength to those derived from a large German sample.We assessed the grip strength distribution across age and derived low grip strength cut-off points for men and women (peak mean -2.5 × SD) based on 200,389 German National Cohort (NAKO) participants aged 19-75 years. In 1,012 Cooperative Health Research in the Region of Augsburg (KORA)-Age participants aged 65-93 years, we calculated the age-standardised prevalence of low grip strength and time-dependent sensitivity and specificity for all-cause mortality.Grip strength increased in the third and fourth decade of life and declined afterwards. Calculated cut-off points for low grip strength were 29 kg for men and 18 kg for women. In KORA-Age, the age-standardised prevalence of low grip strength was 1.5× higher for NAKO-derived (17.7%) compared to EWGSOP2 (11.7%) cut-off points. NAKO-derived cut-off points yielded a higher sensitivity and lower specificity for all-cause mortality.Cut-off points for low grip strength from German population-based data were 2 kg higher than the EWGSOP2 cut-off points. Higher cut-off points increase the sensitivity, thereby suggesting an intervention for more patients at risk, while other individuals might receive additional diagnostics/treatment without the urgent need. Research on the effectiveness of intervention in patients with low grip strength defined by different cut-off points is needed. |
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| 650 | _ | 7 | |a European Working Group on Sarcopenia in Older People (EWGSOP) |2 Other |
| 650 | _ | 7 | |a cut-off points |2 Other |
| 650 | _ | 7 | |a grip strength |2 Other |
| 650 | _ | 7 | |a mortality |2 Other |
| 650 | _ | 7 | |a probable sarcopenia |2 Other |
| 700 | 1 | _ | |a Kluttig, Alexander |b 1 |
| 700 | 1 | _ | |a Fischer, Beate |b 2 |
| 700 | 1 | _ | |a Ahrens, Wolfgang |b 3 |
| 700 | 1 | _ | |a Castell, Stefanie |b 4 |
| 700 | 1 | _ | |a Ebert, Nina |b 5 |
| 700 | 1 | _ | |a Gastell, Sylvia |b 6 |
| 700 | 1 | _ | |a Jöckel, Karl-Heinz |b 7 |
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| 700 | 1 | _ | |a Karch, André |b 9 |
| 700 | 1 | _ | |a Keil, Thomas |b 10 |
| 700 | 1 | _ | |a Kemmling, Yvonne |b 11 |
| 700 | 1 | _ | |a Krist, Lilian |b 12 |
| 700 | 1 | _ | |a Leitzmann, Michael |b 13 |
| 700 | 1 | _ | |a Lieb, Wolfgang |b 14 |
| 700 | 1 | _ | |a Meinke-Franze, Claudia |b 15 |
| 700 | 1 | _ | |a Michels, Karin B |b 16 |
| 700 | 1 | _ | |a Mikolajczyk, Rafael |0 0000-0002-3125-7859 |b 17 |
| 700 | 1 | _ | |a Moreno Velásquez, Ilais |b 18 |
| 700 | 1 | _ | |a Pischon, Tobias |b 19 |
| 700 | 1 | _ | |a Schipf, Sabine |b 20 |
| 700 | 1 | _ | |a Schmidt, Börge |b 21 |
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| 700 | 1 | _ | |a Teismann, Henning |b 25 |
| 700 | 1 | _ | |a Wirkner, Kerstin |b 26 |
| 700 | 1 | _ | |a Drey, Michael |b 27 |
| 700 | 1 | _ | |a Peters, Annette |b 28 |
| 700 | 1 | _ | |a Thorand, Barbara |0 0000-0002-5667-6849 |b 29 |
| 773 | _ | _ | |a 10.1093/ageing/afac324 |g Vol. 52, no. 1, p. afac324 |0 PERI:(DE-600)2065766-3 |n 1 |p afac324 |t Age & ageing |v 52 |y 2023 |x 0002-0729 |
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