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@ARTICLE{Reuss:212546,
author = {D. E. Reuss$^*$},
title = {{U}pdates on the {WHO} diagnosis of {IDH}-mutant glioma.},
journal = {Journal of neuro-oncology},
volume = {162},
number = {3},
issn = {0167-594x},
address = {Dordrecht [u.a.]},
publisher = {Springer Science + Business Media B.V},
reportid = {DKFZ-2023-00231},
pages = {461-469},
year = {2023},
note = {#LA:B300# / 2023 May;162(3):461-469},
abstract = {The WHO classification of Tumors of the Central Nervous
System represents the international standard classification
for brain tumors. In 2021 the 5th edition (WHO CNS5) was
published, and this review summarizes the changes regarding
IDH-mutant gliomas and discusses unsolved issues and future
perspectives.This review is based on the 5th edition of the
WHO Blue Book of CNS tumors (WHO CNS5) and relevant related
papers.Major changes include taxonomy and nomenclature of
IDH-mutant gliomas. Essential and desirable criteria for
classification were established considering technical
developments. For the first time molecular features are not
only relevant for the classification of IDH-mutant gliomas
but may impact grading as well.WHO CNS5 classification moves
forward towards a classification which is founded on tumor
biology and serves clinical needs. The rapidly increasing
knowledge on the molecular landscape of IDH-mutant gliomas
is expected to further refine classification and grading in
the future.},
subtyp = {Review Article},
keywords = {CNS5 (Other) / Classification (Other) / Glioma (Other) /
IDH-mutant (Other) / Molecular pathology (Other) /
Neuropathology (Other) / WHO (Other)},
cin = {B300 / HD01},
ddc = {610},
cid = {I:(DE-He78)B300-20160331 / I:(DE-He78)HD01-20160331},
pnm = {312 - Funktionelle und strukturelle Genomforschung
(POF4-312)},
pid = {G:(DE-HGF)POF4-312},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:36717507},
doi = {10.1007/s11060-023-04250-5},
url = {https://inrepo02.dkfz.de/record/212546},
}