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000267549 1001_ $$0P:(DE-He78)d7135c1486ffd923f71735d40a3d7a0c$$aRotkopf, Lukas Thomas$$b0$$eFirst author$$udkfz
000267549 245__ $$aInfluence of heart rate and heart rate variability on the feasibility of ultra-fast, high-pitch coronary photon-counting computed tomography angiography.
000267549 260__ $$aDordrecht [u.a.]$$bSpringer$$c2023
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000267549 500__ $$a#EA:E010# / 2023 May;39(5):1065-1073
000267549 520__ $$aCoronary computed tomography angiography has become a mainstay in diagnosing coronary artery disease and is increasingly used in screening symptomatic patients. Recently, photon-counting computed tomography (PCCT) has been introduced into clinical practice, offering higher spatial and temporal resolution. As the applied radiation dose is highly dependent on the choice of scan mode and is lowest using the ultra-fast high-pitch (FLASH) mode, guidelines for their application are needed. From a retrospective study investigating the properties of a novel photon-counting computed tomography, all patients who underwent FLASH-mode PCCT angiography were selected between January and April 2022. This resulted in a study population of 46 men and 27 women. We recorded pre- and intrascan ECG readings and calculated heart rate (maximum heart rate 73 bpm) as well heart rate variability (maximum HRV 37 bpm) as measured by the standard deviation of the heart rate. Diagnostic quality and motion artifacts scores were recorded for each coronary artery segment by consensus between two readers. We found a highly significant association between heart rate variability and image quality (p < 0.001). The heart rate itself was not independently associated with image quality. Both heart rate and heart rate variability were significantly associated with the presence of motion artifacts in a combined model. Scan heart rate variability-but not heart rate itself-is a highly significant predictor of reduced image quality on high-pitch coronary photon-counting computed tomography angiography. This may be due to better scanner architecture and an increased temporal resolution compared to conventional energy-integrating detector computed tomography, which has to be addressed in a comparison study in the future.
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000267549 650_7 $$2Other$$aDose reduction
000267549 650_7 $$2Other$$aFLASH mode
000267549 650_7 $$2Other$$aHeart rate
000267549 650_7 $$2Other$$aImage quality
000267549 650_7 $$2Other$$aPhoton-counting detector CT
000267549 7001_ $$aFroelich, Matthias F$$b1
000267549 7001_ $$aRiffel, Philipp$$b2
000267549 7001_ $$0P:(DE-He78)a56941777fbaf0ca1008366e7e16667f$$aZiener, Christian H$$b3$$udkfz
000267549 7001_ $$0P:(DE-He78)a06ba45fcf672f893e3d0946fe3f3483$$aReid, Carissa$$b4$$udkfz
000267549 7001_ $$0P:(DE-He78)3d04c8fee58c9ab71f62ff80d06b6fec$$aSchlemmer, Heinz-Peter$$b5$$udkfz
000267549 7001_ $$aSchoenberg, Stefan O$$b6
000267549 7001_ $$aAyx, Isabelle$$b7
000267549 773__ $$0PERI:(DE-600)2008950-8$$a10.1007/s10554-023-02808-y$$n5$$p1065-1073$$tThe international journal of cardiovascular imaging$$v39$$x0167-9899$$y2023
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