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@ARTICLE{Saul:267567,
      author       = {P. Saul and L. Schröder$^*$ and A. Schmidt$^*$ and J.-B.
                      Hövener},
      title        = {{N}anomaterials for hyperpolarized nuclear magnetic
                      resonance and magnetic resonance imaging.},
      journal      = {Wiley interdisciplinary reviews / Nanomedicine and
                      Nanobiotechnology},
      volume       = {15},
      number       = {4},
      issn         = {1939-5116},
      address      = {Malden, MA},
      publisher    = {Wiley-Blackwell},
      reportid     = {DKFZ-2023-00345},
      pages        = {e1879},
      year         = {2023},
      note         = {2023 Jul-Aug;15(4):e1879},
      abstract     = {Nanomaterials play an important role in the development and
                      application of hyperpolarized materials for magnetic
                      resonance imaging (MRI). In this context they can not only
                      act as hyperpolarized materials which are directly imaged
                      but also play a role as carriers for hyperpolarized gases
                      and catalysts for para-hydrogen induced polarization (PHIP)
                      to generate hyperpolarized substrates for metabolic imaging.
                      Those three application possibilities are discussed,
                      focusing on carbon-based materials for the directly imaged
                      particles. An overview over recent developments in all three
                      fields is given, including the early developments in each
                      field as well as important steps towards applications in
                      MRI, such as making the initially developed methods more
                      biocompatible and first imaging experiments with spatial
                      resolution in either phantoms or in vivo studies. Focusing
                      on the important features nanomaterials need to display to
                      be applicable in the MRI context, a wide range of different
                      approaches to that extent is covered, giving the reader a
                      general idea of different possibilities as well as recent
                      developments in those different fields of hyperpolarized
                      magnetic resonance. This article is categorized under:
                      Therapeutic Approaches and Drug Discovery > Emerging
                      Technologies Diagnostic Tools > In Vivo Nanodiagnostics and
                      Imaging.},
      subtyp        = {Review Article},
      keywords     = {hyperpolarization (Other) / magnetic resonance imaging
                      (MRI) (Other) / nuclear magnetic resonance (NMR) (Other)},
      cin          = {E280 / FR01},
      ddc          = {570},
      cid          = {I:(DE-He78)E280-20160331 / I:(DE-He78)FR01-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:36781151},
      doi          = {10.1002/wnan.1879},
      url          = {https://inrepo02.dkfz.de/record/267567},
}