Journal Article (Review Article)

DKFZ-2023-00345

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Nanomaterials for hyperpolarized nuclear magnetic resonance and magnetic resonance imaging.

Saul, P. ; Schröder, L.DKFZ* ; Schmidt, A.DKFZ* ; Hövener, J.-B.

2023
Wiley-Blackwell Malden, MA

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Please use a persistent id in citations: doi:10.1002/wnan.1879

Abstract: Nanomaterials play an important role in the development and application of hyperpolarized materials for magnetic resonance imaging (MRI). In this context they can not only act as hyperpolarized materials which are directly imaged but also play a role as carriers for hyperpolarized gases and catalysts for para-hydrogen induced polarization (PHIP) to generate hyperpolarized substrates for metabolic imaging. Those three application possibilities are discussed, focusing on carbon-based materials for the directly imaged particles. An overview over recent developments in all three fields is given, including the early developments in each field as well as important steps towards applications in MRI, such as making the initially developed methods more biocompatible and first imaging experiments with spatial resolution in either phantoms or in vivo studies. Focusing on the important features nanomaterials need to display to be applicable in the MRI context, a wide range of different approaches to that extent is covered, giving the reader a general idea of different possibilities as well as recent developments in those different fields of hyperpolarized magnetic resonance. This article is categorized under: Therapeutic Approaches and Drug Discovery > Emerging Technologies Diagnostic Tools > In Vivo Nanodiagnostics and Imaging.

Keyword(s): hyperpolarization ; magnetic resonance imaging (MRI) ; nuclear magnetic resonance (NMR)

Note: 2023 Jul-Aug;15(4):e1879

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Contributing Institute(s):

1. Translationale Molekulare Bildgebung (E280)
2. DKTK Koordinierungsstelle Freiburg (FR01)

Research Program(s):

1. 315 - Bildgebung und Radioonkologie (POF4-315) (POF4-315)

Appears in the scientific report 2023

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Database coverage:
; BIOSIS Previews ; BIOSIS Reviews Reports And Meetings ; Clarivate Analytics Master Journal List ; DEAL Wiley ; Essential Science Indicators ; IF >= 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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