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@ARTICLE{Winkelkotte:274430,
      author       = {A. Winkelkotte$^*$ and A. Schulze$^*$},
      title        = {{P}almitate paves the way to lung metastasis.},
      journal      = {Trends in cancer},
      volume       = {9},
      number       = {5},
      issn         = {2405-8033},
      address      = {Amsterdam},
      publisher    = {Elsevier},
      reportid     = {DKFZ-2023-00594},
      pages        = {376-378},
      year         = {2023},
      note         = {#EA:A410#LA:A410# / 2023 May;9(5):376-378 / Spotlight},
      abstract     = {New findings by Altea-Manzano et al. demonstrate that
                      primary breast tumours or a high-fat diet induce palmitate
                      secretion by alveolar type 2 (AT2) cells to prepare a
                      premetastatic niche that promotes lung metastasis. Palmitate
                      is utilised by cancer cells via carnitine
                      palmitoyltransferase 1a (CPT1a) and lysine acetyltransferase
                      2a (KAT2a) to acetylate nuclear factor-κB (NF-κB)/p65.
                      Blocking these enzymes reduced metastasis formation in both
                      lean and high-fat diet mice.},
      keywords     = {NF-kB (Other) / breast cancer (Other) / lung metastasis
                      (Other) / palmitate (Other) / premetastatic niche (Other) /
                      protein acetylation (Other)},
      cin          = {A410},
      ddc          = {610},
      cid          = {I:(DE-He78)A410-20160331},
      pnm          = {311 - Zellbiologie und Tumorbiologie (POF4-311)},
      pid          = {G:(DE-HGF)POF4-311},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:36959035},
      doi          = {10.1016/j.trecan.2023.03.001},
      url          = {https://inrepo02.dkfz.de/record/274430},
}