%0 Journal Article
%A Venkataramani, Varun
%T IGSF3-mediated potassium dysregulation promotes neuronal hyperexcitability and glioma progression.
%J Trends in cancer
%V 9
%N 6
%@ 2405-8033
%C Amsterdam
%I Elsevier
%M DKFZ-2023-00826
%P 457-458
%D 2023
%Z #LA:B320# / 2023 Jun;9(6):457-458
%X Glioblastomas are incurable tumors often associated with epileptic seizures. In a recent study published in Neuron,Curry et al. demonstrated a novel function of the membrane protein IGSF3 that induces potassium dysregulation, neuronal hyperexcitability, and tumor progression. This work uncovers a novel layer of bidirectional neuron-tumor communication, further underlining the importance of comprehensively investigating neuron-tumor networks in glioblastoma.
%K cancer neuroscience (Other)
%K glioblastoma (Other)
%K neuro-oncology (Other)
%K neuronal hyperexcitability (Other)
%K neuron–tumor networks (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37100731
%R 10.1016/j.trecan.2023.04.005
%U https://inrepo02.dkfz.de/record/275624