TY  - JOUR
AU  - Venkataramani, Varun
TI  - IGSF3-mediated potassium dysregulation promotes neuronal hyperexcitability and glioma progression.
JO  - Trends in cancer
VL  - 9
IS  - 6
SN  - 2405-8033
CY  - Amsterdam
PB  - Elsevier
M1  - DKFZ-2023-00826
SP  - 457-458
PY  - 2023
N1  - #LA:B320# / 2023 Jun;9(6):457-458
AB  - Glioblastomas are incurable tumors often associated with epileptic seizures. In a recent study published in Neuron,Curry et al. demonstrated a novel function of the membrane protein IGSF3 that induces potassium dysregulation, neuronal hyperexcitability, and tumor progression. This work uncovers a novel layer of bidirectional neuron-tumor communication, further underlining the importance of comprehensively investigating neuron-tumor networks in glioblastoma.
KW  - cancer neuroscience (Other)
KW  - glioblastoma (Other)
KW  - neuro-oncology (Other)
KW  - neuronal hyperexcitability (Other)
KW  - neuron–tumor networks (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:37100731
DO  - DOI:10.1016/j.trecan.2023.04.005
UR  - https://inrepo02.dkfz.de/record/275624
ER  -