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@ARTICLE{Campa:275974,
author = {D. Campa and M. Gentiluomo and A. Stein$^*$ and M. N. Aoki
and M. Oliverius and L. Vodičková and K. Jamroziak and G.
Theodoropoulos and C. Pasquali and W. Greenhalf and P. G.
Arcidiacono and F. Uzunoglu and R. Pezzilli and C. Luchini
and M. Puzzono and M. Loos and M. Giaccherini and V.
Katzke$^*$ and A. Mambrini and E. Kiudeliene and K. E.
Federico and J. Johansen and T. Hussein and B.
Mohelnikova-Duchonova and C. H. J. van Eijck and H.
Brenner$^*$ and R. Farinella and J. S. Pérez and M. Lovecek
and M. W. Büchler and V. Hlavac and J. R. Izbicki and T.
Hackert and R. Chammas and A. Zerbi and R. Lawlor and A.
Felici and M. Götz and G. Capurso and L. Ginocchi and M.
Gazouli and J. Kupcinskas and G. M. Cavestro and P. Vodicka
and S. Moz and J. P. Neoptolemos and L. Kunovsky and S. E.
Bojesen and S. Carrara and D. Gioffreda and E. Morkunas and
O. Abian and S. Bunduc and D. Basso and U. Boggi and B.
Wlodarczyk and A. Szentesi and G. Vanella and I. Chen and M.
F. Bijlsma and V. Kiudelis and S. Landi and B.
Schöttker$^*$ and C. Corradi and N. Giese and R. Kaaks$^*$
and G. Peduzzi and P. Hegyi and L. Morelli and N. Furbetta
and P. Soucek and A. Latiano and R. Talar-Wojnarowska and S.
C. Lindgaard and F. Dijk and A. C. Milanetto and F. Tavano
and K. Cervena and B. Erőss and S. G. Testoni and J. H. E.
Verhagen-Oldenampsen and E. Małecka-Wojciesko and E.
Costello and R. Salvia and E. Maiello and S. Ermini and C.
Sperti and B. Holleczek$^*$ and F. Perri and J.
Skieceviciene and L. Archibugi and M. Lucchesi and C.
Rizzato and F. Canzian$^*$},
title = {{T}he {PAN}creatic {D}isease {R}ese{A}rch ({PAND}o{RA})
consortium: ten years' experience of association studies to
understand the genetic architecture of pancreatic cancer.},
journal = {Critical reviews in oncology, hematology},
volume = {186},
issn = {0737-9587},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {DKFZ-2023-00954},
pages = {104020},
year = {2023},
note = {#LA:C055#},
abstract = {Pancreatic cancer has an incidence that almost matches its
mortality. Only a small number of risk factors and 33
susceptibility loci have been identified. so Moreover, the
relative rarity of pancreatic cancer poses significant
hurdles for research aimed at increasing our knowledge of
the genetic mechanisms contributing to the disease.
Additionally, the inability to adequately power research
questions prevents small monocentric studies from being
successful. Several consortia have been established to
pursue a better understanding of the genetic architecture of
pancreatic cancers. The Pancreatic disease research
(PANDoRA) consortium is the largest in Europe. PANDoRA is
spread across 12 European countries, Brazil and Japan,
bringing together 29 basic and clinical research groups. In
the last ten years, PANDoRA has contributed to the discovery
of 25 susceptibility loci, a feat that will be instrumental
in stratifying the population by risk and optimizing
preventive strategies.},
subtyp = {Review Article},
keywords = {Pancreatic cancer (Other) / chronic pancreatitis (Other) /
consortium (Other) / genetic epidemiology (Other) /
intraductal papillary mucinous neoplasms (Other) /
pancreatic ductal adenocarcinoma (Other) / pancreatic
neuroendocrine tumors (Other)},
cin = {C055 / C020 / C070 / C120 / HD01},
ddc = {610},
cid = {I:(DE-He78)C055-20160331 / I:(DE-He78)C020-20160331 /
I:(DE-He78)C070-20160331 / I:(DE-He78)C120-20160331 /
I:(DE-He78)HD01-20160331},
pnm = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
pid = {G:(DE-HGF)POF4-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:37164172},
doi = {10.1016/j.critrevonc.2023.104020},
url = {https://inrepo02.dkfz.de/record/275974},
}