guest ::
| Home > Publications database > ARID1A mutations in lung cancer: biology, prognostic role, and therapeutic implications. > print |
| Home > Publications database > ARID1A mutations in lung cancer: biology, prognostic role, and therapeutic implications. > print |
| 001 | 276063 | ||
| 005 | 20240229154954.0 | ||
| 024 | 7 | _ | |a 10.1016/j.molmed.2023.04.005 |2 doi |
| 024 | 7 | _ | |a pmid:37179132 |2 pmid |
| 024 | 7 | _ | |a 1471-4914 |2 ISSN |
| 024 | 7 | _ | |a 1471-499X |2 ISSN |
| 024 | 7 | _ | |a altmetric:148237430 |2 altmetric |
| 037 | _ | _ | |a DKFZ-2023-00969 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Jin, Fukang |0 P:(DE-He78)8267c7c8b2e91db98a49f832eb5b99bb |b 0 |e First author |u dkfz |
| 245 | _ | _ | |a ARID1A mutations in lung cancer: biology, prognostic role, and therapeutic implications. |
| 260 | _ | _ | |a Amsterdam [u.a.] |c 2023 |b Elsevier Science |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1690460847_31843 |2 PUB:(DE-HGF) |x Review Article |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 500 | _ | _ | |a #EA:A430#LA:A430# / 2023 Aug;29(8):646-658 |
| 520 | _ | _ | |a Mutations in the AT-interacting domain-rich protein 1A (ARID1A) gene, a critical component of the switch/sucrose nonfermentable (SWI/SNF) complex, are frequently found in most human cancers. Approximately 5-10% of lung cancers carry ARID1A mutations. ARID1A loss in lung cancer correlates with clinicopathological features and poor prognosis. Co-mutation of ARID1A and epidermal growth factor receptor (EGFR) results in the limited efficacy of EGFR tyrosine kinase inhibitors (EGFR-TKIs) but increases the clinical benefit of immune checkpoint inhibitors (ICIs). ARID1A gene mutation plays a role in cell cycle regulation, metabolic reprogramming, and epithelial-mesenchymal transition. We present the first comprehensive review of the relationship between ARID1A gene mutations and lung cancer and discuss the potential of ARID1A as a new molecular target. |
| 536 | _ | _ | |a 311 - Zellbiologie und Tumorbiologie (POF4-311) |0 G:(DE-HGF)POF4-311 |c POF4-311 |f POF IV |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef, PubMed, , Journals: inrepo02.dkfz.de |
| 650 | _ | 7 | |a ARID1A |2 Other |
| 650 | _ | 7 | |a SWI/SNF complex |2 Other |
| 650 | _ | 7 | |a cell cycle regulation |2 Other |
| 650 | _ | 7 | |a epithelial–mesenchymal transition |2 Other |
| 650 | _ | 7 | |a lung cancer |2 Other |
| 650 | _ | 7 | |a metabolic reprogramming |2 Other |
| 700 | 1 | _ | |a Yang, Zhiguang |b 1 |
| 700 | 1 | _ | |a Shao, Jingbo |b 2 |
| 700 | 1 | _ | |a Tao, Jianxin |0 P:(DE-He78)27fb0d2bd2832c8c977e636025736942 |b 3 |u dkfz |
| 700 | 1 | _ | |a Reißfelder, Christoph |b 4 |
| 700 | 1 | _ | |a Loges, Sonja |0 P:(DE-He78)1eee9e84c0f8c90a97fe40b6e8252a23 |b 5 |u dkfz |
| 700 | 1 | _ | |a Zhu, Lei |0 P:(DE-He78)0116f5652cc0dbf455e3aa3914740230 |b 6 |u dkfz |
| 700 | 1 | _ | |a Schölch, Sebastian |0 P:(DE-He78)a9d57fe3333789705a9ceb9ca904e83e |b 7 |e Last author |u dkfz |
| 773 | _ | _ | |a 10.1016/j.molmed.2023.04.005 |g p. S1471491423000758 |0 PERI:(DE-600)2155736-6 |n 8 |p 646-658 |t Trends in molecular medicine |v 29 |y 2023 |x 1471-4914 |
| 909 | C | O | |p VDB |o oai:inrepo02.dkfz.de:276063 |
| 910 | 1 | _ | |a Deutsches Krebsforschungszentrum |0 I:(DE-588b)2036810-0 |k DKFZ |b 0 |6 P:(DE-He78)8267c7c8b2e91db98a49f832eb5b99bb |
| 910 | 1 | _ | |a Deutsches Krebsforschungszentrum |0 I:(DE-588b)2036810-0 |k DKFZ |b 3 |6 P:(DE-He78)27fb0d2bd2832c8c977e636025736942 |
| 910 | 1 | _ | |a Deutsches Krebsforschungszentrum |0 I:(DE-588b)2036810-0 |k DKFZ |b 5 |6 P:(DE-He78)1eee9e84c0f8c90a97fe40b6e8252a23 |
| 910 | 1 | _ | |a Deutsches Krebsforschungszentrum |0 I:(DE-588b)2036810-0 |k DKFZ |b 6 |6 P:(DE-He78)0116f5652cc0dbf455e3aa3914740230 |
| 910 | 1 | _ | |a Deutsches Krebsforschungszentrum |0 I:(DE-588b)2036810-0 |k DKFZ |b 7 |6 P:(DE-He78)a9d57fe3333789705a9ceb9ca904e83e |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Krebsforschung |1 G:(DE-HGF)POF4-310 |0 G:(DE-HGF)POF4-311 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-300 |4 G:(DE-HGF)POF |v Zellbiologie und Tumorbiologie |x 0 |
| 914 | 1 | _ | |y 2023 |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0113 |2 StatID |b Science Citation Index Expanded |d 2022-11-11 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0160 |2 StatID |b Essential Science Indicators |d 2022-11-11 |
| 915 | _ | _ | |a JCR |0 StatID:(DE-HGF)0100 |2 StatID |b TRENDS MOL MED : 2022 |d 2023-10-25 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |d 2023-10-25 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |d 2023-10-25 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0600 |2 StatID |b Ebsco Academic Search |d 2023-10-25 |
| 915 | _ | _ | |a Peer Review |0 StatID:(DE-HGF)0030 |2 StatID |b ASC |d 2023-10-25 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Clarivate Analytics Master Journal List |d 2023-10-25 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1050 |2 StatID |b BIOSIS Previews |d 2023-10-25 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |d 2023-10-25 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1030 |2 StatID |b Current Contents - Life Sciences |d 2023-10-25 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1120 |2 StatID |b BIOSIS Reviews Reports And Meetings |d 2023-10-25 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1110 |2 StatID |b Current Contents - Clinical Medicine |d 2023-10-25 |
| 915 | _ | _ | |a IF >= 10 |0 StatID:(DE-HGF)9910 |2 StatID |b TRENDS MOL MED : 2022 |d 2023-10-25 |
| 920 | 2 | _ | |0 I:(DE-He78)A430-20160331 |k A430 |l NWG-KKE Translationale Chirurgische Onkologie |x 0 |
| 920 | 1 | _ | |0 I:(DE-He78)A430-20160331 |k A430 |l NWG-KKE Translationale Chirurgische Onkologie |x 0 |
| 920 | 1 | _ | |0 I:(DE-He78)A420-20160331 |k A420 |l Personalisierte Medizinische Onkologie |x 1 |
| 920 | 0 | _ | |0 I:(DE-He78)A430-20160331 |k A430 |l NWG-KKE Translationale Chirurgische Onkologie |x 0 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-He78)A430-20160331 |
| 980 | _ | _ | |a I:(DE-He78)A420-20160331 |
| 980 | _ | _ | |a UNRESTRICTED |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|