% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Skarga:276103,
      author       = {E. Skarga$^*$ and H.-M. Surcel and R. Kaaks$^*$ and T.
                      Waterboer$^*$ and R. Turzanski-Fortner$^*$},
      title        = {{S}exually transmitted infections and risk of epithelial
                      ovarian cancer: results from the {F}innish {M}aternity
                      {C}ohort.},
      journal      = {The journal of infectious diseases},
      volume       = {228},
      number       = {11},
      issn         = {0022-1899},
      address      = {Oxford [u.a.]},
      publisher    = {Oxford Univ. Press},
      reportid     = {DKFZ-2023-01003},
      pages        = {1621-1629},
      year         = {2023},
      note         = {#EA:C020#LA:C020# / 2023 Nov 28;228(11):1621-1629},
      abstract     = {Sexually transmitted infections, specifically Chlamydia
                      trachomatis (CT), may be associated with epithelial ovarian
                      cancer (EOC) risk. The association between CT and EOC
                      subtypes is unclear. Our aim was to investigate whether
                      history of CT and other infections (M. genitalium (MG),
                      herpes simplex virus type 2, and human papillomaviruses) are
                      associated with EOC risk by histotype.We measured antibodies
                      (Ab) to CT, MG, HSV2, and HPV-16 and 18 in serum samples in
                      a nested case-control study in the Finnish Maternity Cohort
                      (n= 484 cases 1:1 matched to controls). Logistic Regression
                      was used to calculate relative risks (RRs) and $95\%$
                      confidence intervals [CIs] in seropositive vs. seronegative
                      individuals in all cases, as well as serous (n=249), clear
                      cell and endometrioid (n=91), and mucinous (n=142)
                      EOC.CT-seropositivity was not associated with EOC risk
                      (e.g., CT pGP3-Ab RR=0.92 [0.72- 1.19]), regardless of
                      disease subtype. We observed a positive association between
                      MG-seropositivity and mucinous EOC (RR=1.66 [1.09-2.54];
                      $p-het_histotype≤0.001),$ but not other subtypes. No
                      associations were observed with seropositivity to multiple
                      STIs.CT infection was not associated with EOC risk, with
                      associations observed only for MG and mucinous EOC.
                      Mechanisms linking MG to mucinous EOC remain to be
                      elucidated.},
      keywords     = {Chlamydia Trachomatis (Other) / Ovarian Cancer (Other) /
                      Risk (Other) / Serology (Other) / Sexually Transmitted
                      Infections (Other)},
      cin          = {C020 / F020},
      ddc          = {610},
      cid          = {I:(DE-He78)C020-20160331 / I:(DE-He78)F020-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:37196097},
      doi          = {10.1093/infdis/jiad171},
      url          = {https://inrepo02.dkfz.de/record/276103},
}