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@ARTICLE{Gudenkauf:276415,
author = {L. M. Gudenkauf and M. N. Chavez and M. L. Maconi and C.
Geiss and A. Seyedroudbari and P. Thin and A. I. Hoogland
and K. Nguyen and V. Murthy and W. R. Armstrong and K.
Komrokji and L. B. Oswald and H. S. L. Jim and G. El-Haddad
and W. P. Fendler$^*$ and K. Herrmann$^*$ and D. Cella and
J. Czernin and M. S. Hofman and A. P. Dicker and J. Calais
and S. T. Tagawa and B. D. Gonzalez},
title = {{D}eveloping a {P}atient-{R}eported {O}utcome {M}easure for
{R}adionuclide {T}herapy for {P}rostate {C}ancer.},
journal = {Journal of nuclear medicine},
volume = {64},
number = {6},
issn = {0097-9058},
address = {New York, NY},
publisher = {Soc.},
reportid = {DKFZ-2023-01098},
pages = {869 - 872},
year = {2023},
abstract = {The field of radionuclide therapy (RNT) for prostate cancer
(PC) is growing rapidly, with recent Food and Drug
Administration approval of the first 177Lu-PSMA ligand. We
aimed to develop the first patient-reported outcome (PRO)
measure for PC patients receiving RNT. Methods: We
identified relevant symptoms and toxicities by reviewing
published trials and interviews with PC patients receiving
RNT (n = 29), caregivers (n = 14), and clinicians (n = 11).
Second, we selected items for measure inclusion. Third, we
refined the item list with input from experts in RNTs and
PROs. Fourth, we finalized the Functional Assessment of
Cancer Therapy-Radionuclide Therapy (FACT-RNT) with patient
input. Results: This multistep process yielded a brief
15-item measure deemed by key stakeholders to be relevant
and useful in the context of RNT for PC. Conclusion: The
FACT-RNT is a new standardized tool to monitor relevant
symptoms and toxicities among PC patients in RNT trials and
real-world settings.},
keywords = {Male / Humans / Prostatic Neoplasms: radiotherapy /
Prostatic Neoplasms: drug therapy / Radioisotopes:
therapeutic use / Patient Reported Outcome Measures /
genitourinary oncology (Other) / patient-reported outcomes
(Other) / prostate cancer (Other) / radionuclide therapy
(Other) / radiopharmaceuticals (Other) / Radioisotopes (NLM
Chemicals)},
cin = {ED01},
ddc = {610},
cid = {I:(DE-He78)ED01-20160331},
pnm = {899 - ohne Topic (POF4-899)},
pid = {G:(DE-HGF)POF4-899},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:36635088},
doi = {10.2967/jnumed.122.264946},
url = {https://inrepo02.dkfz.de/record/276415},
}