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@ARTICLE{Ebersberger:277355,
      author       = {L. Ebersberger$^*$ and F. J. Kratzer$^*$ and A. Potreck and
                      S. Niesporek$^*$ and M. Keymling$^*$ and A. M. Nagel$^*$ and
                      M. Bendszus and W. Wick and M. E. Ladd$^*$ and H.-P.
                      Schlemmer$^*$ and A. Hoffmann and T. Platt$^*$ and D.
                      Paech$^*$},
      title        = {{F}irst application of dynamic oxygen-17 magnetic resonance
                      imaging at 7 {T}esla in a patient with early subacute
                      stroke.},
      journal      = {Frontiers in neuroscience},
      volume       = {17},
      issn         = {1662-4548},
      address      = {Lausanne},
      publisher    = {Frontiers Research Foundation},
      reportid     = {DKFZ-2023-01361},
      pages        = {1186558},
      year         = {2023},
      note         = {#EA:E010#LA:E010#LA:E020#},
      abstract     = {Dynamic oxygen-17 (17O) magnetic resonance imaging (MRI) is
                      an imaging method that enables a direct and non-invasive
                      assessment of cerebral oxygen metabolism and thus
                      potentially the distinction between viable and non-viable
                      tissue employing a three-phase inhalation experiment. The
                      purpose of this investigation was the first application of
                      dynamic 17O MRI at 7 Tesla (T) in a patient with stroke. In
                      this proof-of-concept experiment, dynamic 17O MRI was
                      applied during 17O inhalation in a patient with early
                      subacute stroke. The analysis of the relative 17O water
                      (H217O) signal for the affected stroke region compared to
                      the healthy contralateral side revealed no significant
                      difference. However, the technical feasibility of 17O MRI
                      has been demonstrated paving the way for future
                      investigations in neurovascular diseases.},
      keywords     = {7 Tesla (Other) / metabolic imaging (Other) / oxygen
                      metabolism (Other) / oxygen-17 MRI (Other) / stroke (Other)
                      / ultra-high field (Other)},
      cin          = {E010 / E020},
      ddc          = {610},
      cid          = {I:(DE-He78)E010-20160331 / I:(DE-He78)E020-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:37404469},
      pmc          = {pmc:PMC10317041},
      doi          = {10.3389/fnins.2023.1186558},
      url          = {https://inrepo02.dkfz.de/record/277355},
}