guest ::
| Home > Publications database > Early mortality critically impedes improvements in thyroid cancer survival through a half century. |
| Home > Publications database > Early mortality critically impedes improvements in thyroid cancer survival through a half century. |
| Journal Article | DKFZ-2023-01827 |
; ; ; ; ; ;
2023
BioScientifica Ltd.
Bristol
This record in other databases: 
Please use a persistent id in citations: doi:10.1093/ejendo/lvad117
Abstract: We analyze survival in thyroid cancer from Denmark (DK), Finland (FI), Norway (NO), and Sweden (SE) over a 50-year period (1971-2020), and additionally consider concomitant changes in incidence and mortality.Population-based survival study.Relative 1-, 5/1 (conditional)-, and 5-year survival data were obtained from the NORDCAN database for years 1971-2020. Incidence and mortality rates were also assessed.A novel consistent observation was that 1-year survival was worse than 5/1-year survival but the difference between these decreased with time. Relative 1-year survival in thyroid cancer (mean for the 4 countries) reached 92.7% for men and 95.6% for women; 5-year survival reached 88.0% for men and 93.7% for women. Survival increased most for DK which started at a low level and reached the best survival at the end. Male and female incidence rates for thyroid cancer increased 3- and 4-fold, respectively. In the same time, mortality halved for men and for women, it decreased by 2/3.We documented worse relative survival in the first year than in the 4 subsequent years, most likely because of rare anaplastic cancer. Overall survival in thyroid cancer patients increased in the Nordic countries in the course of 50 years; 5-year survival was close to 90% for men and close to 95% for women. Even though overdiagnosis may explain some of 5-year survival increase, it is unlikely to influence the substantial increase in 1-year survival. The unmet need is to increase 1-year survival by diagnosing and treating aggressive tumors before metastatic spread.
Keyword(s): Female (MeSH) ; Humans (MeSH) ; Male (MeSH) ; Thyroid Neoplasms: diagnosis (MeSH) ; Thyroid Neoplasms: epidemiology (MeSH) ; Databases, Factual (MeSH) ; Finland: epidemiology (MeSH) ; Norway: epidemiology (MeSH) ; anaplastic cancer ; diagnostics ; relative survival ; treatment
; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Current Contents - Life Sciences ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
|
The record appears in these collections: |
