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000285285 1001_ $$aZhang, Ke$$b0
000285285 245__ $$aSimultaneous T1, T2 and T2⁎ mapping of the liver with multi-shot MI-SAGE.
000285285 260__ $$aAmsterdam [u.a.]$$bElsevier Science$$c2024
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000285285 520__ $$aTo apply multi-shot high-resolution multi inversion spin and gradient echo (MI-SAGE) acquisition for simultaneous liver T1, T2 and T2* mapping.Inversion prepared spin- and gradient-echo EPI was developed with ascending slice order across measurements for efficient acquisition with T1, T2, and T2⁎ weighting. Multi-shot EPI was also implemented to minimize distortion and blurring while enabling high in-plane resolution. A dictionary-matching approach was used to fit the images to quantitative parameter maps, which were compared to T1 measured by modified Look-Locker (MOLLI), T1 measured by variable flip angle (VFA), T2 measured by multiple echo time-based Half Fourier Single-shot Turbo spin-Echo (HASTE), T2 measured by radial turbo-spin-echo (rTSE) and T2⁎ measured by multiple gradient echo (MGRE) sequences.The multi-shot variant of the sequence achieved higher in-plane resolution of 1.7 × 1.7 mm2 with good image quality in 28 s. Derived quantitative maps showed comparable values to conventional mapping methods. As measured in phantom and in vivo, MOLLI, MESE and MGRE give closest values to MISAGE. VFA, HASTE and rTSE show obvious overestimation.The proposed multi-shot inversion prepared spin- and gradient-echo EPI sequence allows for high-resolution quantitative T1, T2 and T2 liver tissue characterization in a single breath-hold scan.
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000285285 650_7 $$2Other$$aLiver
000285285 650_7 $$2Other$$aMulti inversion spin and gradient echo
000285285 650_7 $$2Other$$aMulti-shot acquisitions
000285285 650_7 $$2Other$$aParametric mapping
000285285 7001_ $$aTriphan, Simon M F$$b1
000285285 7001_ $$aWielpütz, Mark O$$b2
000285285 7001_ $$0P:(DE-He78)a56941777fbaf0ca1008366e7e16667f$$aZiener, Christian H$$b3$$udkfz
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000285285 7001_ $$0P:(DE-He78)3d04c8fee58c9ab71f62ff80d06b6fec$$aSchlemmer, Heinz-Peter$$b5$$udkfz
000285285 7001_ $$aKauczor, Hans-Ulrich$$b6
000285285 7001_ $$0P:(DE-He78)ea7f20e71e3cb1a864c23f2f09f0b0b9$$aKurz, Felix T$$b7$$udkfz
000285285 7001_ $$0P:(DE-He78)82090937e7b88ac8ec70bbc40ad6b512$$aSedlaczek, Oliver$$b8$$eLast author$$udkfz
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