TY  - JOUR
AU  - Morales-Berstein, Fernanda
AU  - Biessy, Carine
AU  - Viallon, Vivian
AU  - Goncalves-Soares, Ana
AU  - Casagrande, Corinne
AU  - Hémon, Bertrand
AU  - Kliemann, Nathalie
AU  - Cairat, Manon
AU  - Blanco Lopez, Jessica
AU  - Al Nahas, Aline
AU  - Chang, Kiara
AU  - Vamos, Eszter
AU  - Rauber, Fernanda
AU  - Bertazzi Levy, Renata
AU  - Barbosa Cunha, Diana
AU  - Jakszyn, Paula
AU  - Ferrari, Pietro
AU  - Vineis, Paolo
AU  - Masala, Giovanna
AU  - Catalano, Alberto
AU  - Sonestedt, Emily
AU  - Borné, Yan
AU  - Katzke, Verena
AU  - Bajracharya, Rashmita
AU  - Agnoli, Claudia
AU  - Guevara, Marcela
AU  - Heath, Alicia
AU  - Radoï, Loredana
AU  - Mancini, Francesca
AU  - Weiderpass, Elisabete
AU  - Huerta, José María
AU  - Sánchez, María-José
AU  - Tjønneland, Anne
AU  - Kyrø, Cecilie
AU  - Schulze, Matthias B
AU  - Skeie, Guri
AU  - Lukic, Marko
AU  - Braaten, Tonje
AU  - Gunter, Marc
AU  - Millett, Christopher
AU  - Agudo, Antonio
AU  - Brennan, Paul
AU  - Borges, M Carolina
AU  - Richmond, Rebecca C
AU  - Richardson, Tom G
AU  - Davey Smith, George
AU  - Relton, Caroline L
AU  - Huybrechts, Inge
TI  - Ultra-processed foods, adiposity and risk of head and neck cancer and oesophageal adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition study: a mediation analysis.
JO  - European journal of nutrition
VL  - 63
IS  - 2
SN  - 1436-6207
CY  - Heidelberg
PB  - Springer
M1  - DKFZ-2023-02406
SP  - 377-396
PY  - 2024
N1  - 2024 Mar;63(2):377-396
AB  - To investigate the role of adiposity in the associations between ultra-processed food (UPF) consumption and head and neck cancer (HNC) and oesophageal adenocarcinoma (OAC) in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.Our study included 450,111 EPIC participants. We used Cox regressions to investigate the associations between the consumption of UPFs and HNC and OAC risk. A mediation analysis was performed to assess the role of body mass index (BMI) and waist-to-hip ratio (WHR) in these associations. In sensitivity analyses, we investigated accidental death as a negative control outcome.During a mean follow-up of 14.13 ± 3.98 years, 910 and 215 participants developed HNC and OAC, respectively. A 10
KW  - Adiposity (Other)
KW  - Epidemiology (Other)
KW  - Food processing (Other)
KW  - Head and neck cancer (Other)
KW  - Mediation analysis (Other)
KW  - NOVA classification (Other)
KW  - Oesophageal cancer (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:37989797
DO  - DOI:10.1007/s00394-023-03270-1
UR  - https://inrepo02.dkfz.de/record/285526
ER  -