TY  - JOUR
AU  - Fontvieille, Emma
AU  - Viallon, Vivian
AU  - Recalde, Martina
AU  - Cordova, Reynalda
AU  - Jansana, Anna
AU  - Peruchet-Noray, Laia
AU  - Lennon, Hannah
AU  - Heath, Alicia K
AU  - Aune, Dagfinn
AU  - Christakoudi, Sofia
AU  - Katzke, Verena
AU  - Kaaks, Rudolf
AU  - Inan-Eroglu, Elif
AU  - Schulze, Matthias B
AU  - Mellemkjær, Lene
AU  - Tjønneland, Anne
AU  - Overvad, Kim
AU  - Farràs, Marta
AU  - Petrova, Dafina
AU  - Amiano, Pilar
AU  - Chirlaque, María-Dolores
AU  - Moreno-Iribas, Conchi
AU  - Tin Tin, Sandar
AU  - Masala, Giovanna
AU  - Sieri, Sabina
AU  - Ricceri, Fulvio
AU  - Panico, Salvatore
AU  - May, Anne M
AU  - Monninkhof, Evelyn M
AU  - Weiderpass, Elisabete
AU  - Gunter, Marc J
AU  - Ferrari, Pietro
AU  - Freisling, Heinz
TI  - Body mass index and cancer risk among adults with and without cardiometabolic diseases: evidence from the EPIC and UK Biobank prospective cohort studies.
JO  - BMC medicine
VL  - 21
IS  - 1
SN  - 1741-7015
CY  - Heidelberg [u.a.]
PB  - Springer
M1  - DKFZ-2023-02431
SP  - 418
PY  - 2023
AB  - Whether cancer risk associated with a higher body mass index (BMI), a surrogate measure of adiposity, differs among adults with and without cardiovascular diseases (CVD) and/or type 2 diabetes (T2D) is unclear. The primary aim of this study was to evaluate separate and joint associations of BMI and CVD/T2D with the risk of cancer.This is an individual participant data meta-analysis of two prospective cohort studies, the UK Biobank (UKB) and the European Prospective Investigation into Cancer and nutrition (EPIC), with a total of 577,343 adults, free of cancer, T2D, and CVD at recruitment. We used Cox proportional hazard regressions to estimate multivariable-adjusted hazard ratios (HRs) and 95
KW  - Cardiovascular diseases (Other)
KW  - Comorbidities (Other)
KW  - Multimorbidity (Other)
KW  - Obesity (Other)
KW  - Obesity-related cancers (Other)
KW  - Type 2 diabetes (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:37993940
DO  - DOI:10.1186/s12916-023-03114-z
UR  - https://inrepo02.dkfz.de/record/285565
ER  -