Journal Article (Review Article) DKFZ-2024-00305

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Validation of complex radiotherapy techniques using polymer gel dosimetry.

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2024
IOP Publ. Bristol

Physics in medicine and biology 69(6), 06TR01 () [10.1088/1361-6560/ad278f]
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Abstract: Modern radiotherapy delivers highly conformal dose distributions to irregularly shaped target volumes while sparing the surrounding normal tissue. Due to the complex planning and delivery techniques, dose verification and validation of the whole treatment workflow by end-to-end tests became much more important and polymer gel dosimeters are one of the few possibilities to capture the delivered dose distribution in 3D. The basic principles and formulations of gel dosimetry and its evaluation methods are described and the available studies validating device-specific geometrical parameters as well as the dose delivery by advanced radiotherapy techniques, such as 3D-CRT/IMRT and SRS treatments, the treatment of moving targets, online-adaptive MRgRT as well as proton and ion beam treatments, are reviewed. The present status and limitations as well as future challenges of polymer gel dosimetry for the validation of complex radiotherapy techniques are discussed.

Keyword(s): MR-guided RT ; Polymer gel dosimetry ; adaptive radiotherapy (RT) ; inter- and intrafractional motion ; proton and ion beam RT ; verification of 3D dose distribution

Classification:

Note: Phys. Med. Biol. 69 (2024) 06TR01 / #EA:E040#

Contributing Institute(s):
  1. E040 Med. Physik in der Strahlentherapie (E040)
Research Program(s):
  1. 315 - Bildgebung und Radioonkologie (POF4-315) (POF4-315)

Appears in the scientific report 2024
Database coverage:
Medline ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Ebsco Academic Search ; Essential Science Indicators ; IF < 5 ; JCR ; National-Konsortium ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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 Record created 2024-02-09, last modified 2024-04-22



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