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@ARTICLE{Angelova:289187,
      author       = {A. L. Angelova$^*$ and J. Rommelaere$^*$ and G.
                      Ungerechts$^*$},
      title        = {{T}he {C}omplex {R}ole of {I}nfectious {A}gents in {H}uman
                      {C}utaneous {T}-{C}ell {L}ymphoma {P}athogenesis: {F}rom
                      {C}andidate {E}tiological {F}actors to {P}otential
                      {T}herapeutics.},
      journal      = {Pathogens},
      volume       = {13},
      number       = {3},
      issn         = {2076-0817},
      address      = {Basel},
      publisher    = {MDPI},
      reportid     = {DKFZ-2024-00622},
      pages        = {184},
      year         = {2024},
      note         = {#EA:F230#LA:F230# / NEU #EA:D490#LA:D490#},
      abstract     = {Cutaneous T-cell lymphoma (CTCL) is a devastating,
                      potentially fatal T-lymphocyte malignancy affecting the
                      skin. Despite all efforts, the etiology of this disease
                      remains unknown. Infectious agents have long been suspected
                      as factors or co-factors in CTCL pathogenesis. This review
                      deals with the panel of bacterial and viral pathogens that
                      have been investigated so far in an attempt to establish a
                      potential link between infection/carriage and CTCL
                      development. A special focus is given to a recently
                      discovered human protoparvovirus, namely the cutavirus
                      (CutaV), which has emerged as a plausible CTCL etiological
                      agent. Available evidence in support of this hypothesis as
                      well as alternative interpretations and uncertainties raised
                      by some conflicting data are discussed. The complexity and
                      multifacetedness of the Parvoviridae family of viruses are
                      illustrated by presenting another protoparvovirus, the rat
                      H-1 parvovirus (H-1PV). H-1PV belongs to the same genus as
                      the CutaV but carries considerable potential for therapeutic
                      applications in cutaneous lymphoma.},
      subtyp        = {Review Article},
      keywords     = {Parvoviridae (Other) / cutaneous T-cell lymphoma (Other) /
                      cutavirus (Other) / infectious etiology (Other) / oncolytic
                      H-1 parvovirus (Other)},
      cin          = {F230 / D490},
      ddc          = {610},
      cid          = {I:(DE-He78)F230-20160331 / I:(DE-He78)D490-20160331},
      pnm          = {314 - Immunologie und Krebs (POF4-314)},
      pid          = {G:(DE-HGF)POF4-314},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:38535528},
      doi          = {10.3390/pathogens13030184},
      url          = {https://inrepo02.dkfz.de/record/289187},
}