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000289472 1001_ $$aShu, Jinhui$$b0
000289472 245__ $$aThe enchanting canvas of CAR technology: Unveiling its wonders in non-neoplastic diseases.
000289472 260__ $$aAmsterdam$$bElsevier$$c2024
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000289472 500__ $$a2024 Jun 14;5(6):495-529
000289472 520__ $$aChimeric antigen receptor (CAR) T cells have made a groundbreaking advancement in personalized immunotherapy and achieved widespread success in hematological malignancies. As CAR technology continues to evolve, numerous studies have unveiled its potential far beyond the realm of oncology. This review focuses on the current applications of CAR-based cellular platforms in non-neoplastic indications, such as autoimmune, infectious, fibrotic, and cellular senescence-associated diseases. Furthermore, we delve into the utilization of CARs in non-T cell populations such as natural killer (NK) cells and macrophages, highlighting their therapeutic potential in non-neoplastic conditions and offering the potential for targeted, personalized therapies to improve patient outcomes and enhanced quality of life.
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000289472 650_7 $$2Other$$aCAR
000289472 650_7 $$2Other$$aCAR macrophage
000289472 650_7 $$2Other$$aCAR-NK
000289472 650_7 $$2Other$$aautoimmune diseases
000289472 650_7 $$2Other$$acellular senescence
000289472 650_7 $$2Other$$afibrotic diseases
000289472 650_7 $$2Other$$ainfectious diseases
000289472 7001_ $$aXie, Wei$$b1
000289472 7001_ $$aChen, Zhaozhao$$b2
000289472 7001_ $$0P:(DE-He78)81ae96953d6149e4307057d71a190019$$aOffringa, Rienk$$b3$$udkfz
000289472 7001_ $$aHu, Yu$$b4
000289472 7001_ $$aMei, Heng$$b5
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