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@ARTICLE{Shu:289472,
      author       = {J. Shu and W. Xie and Z. Chen and R. Offringa$^*$ and Y. Hu
                      and H. Mei},
      title        = {{T}he enchanting canvas of {CAR} technology: {U}nveiling
                      its wonders in non-neoplastic diseases.},
      journal      = {Med},
      volume       = {5},
      number       = {6},
      issn         = {2666-6340},
      address      = {Amsterdam},
      publisher    = {Elsevier},
      reportid     = {DKFZ-2024-00794},
      pages        = {495-529},
      year         = {2024},
      note         = {2024 Jun 14;5(6):495-529},
      abstract     = {Chimeric antigen receptor (CAR) T cells have made a
                      groundbreaking advancement in personalized immunotherapy and
                      achieved widespread success in hematological malignancies.
                      As CAR technology continues to evolve, numerous studies have
                      unveiled its potential far beyond the realm of oncology.
                      This review focuses on the current applications of CAR-based
                      cellular platforms in non-neoplastic indications, such as
                      autoimmune, infectious, fibrotic, and cellular
                      senescence-associated diseases. Furthermore, we delve into
                      the utilization of CARs in non-T cell populations such as
                      natural killer (NK) cells and macrophages, highlighting
                      their therapeutic potential in non-neoplastic conditions and
                      offering the potential for targeted, personalized therapies
                      to improve patient outcomes and enhanced quality of life.},
      subtyp        = {Review Article},
      keywords     = {CAR (Other) / CAR macrophage (Other) / CAR-NK (Other) /
                      autoimmune diseases (Other) / cellular senescence (Other) /
                      fibrotic diseases (Other) / infectious diseases (Other)},
      cin          = {D200},
      ddc          = {610},
      cid          = {I:(DE-He78)D200-20160331},
      pnm          = {314 - Immunologie und Krebs (POF4-314)},
      pid          = {G:(DE-HGF)POF4-314},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:38608709},
      doi          = {10.1016/j.medj.2024.03.016},
      url          = {https://inrepo02.dkfz.de/record/289472},
}