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@ARTICLE{Holze:292327,
      author       = {M. Holze and A. Ahmed$^*$ and M. Loos and C. W. Michalski
                      and R. Klotz},
      title        = {{S}ex differences in pancreatic
                      cancer.[{G}eschlechtsunterschiede beim {P}ankreaskarzinom.]},
      journal      = {Die Chirurgie},
      volume       = {95},
      number       = {9},
      issn         = {2731-6971},
      address      = {[Berlin]},
      publisher    = {Springer Medizin Verlag GmbH},
      reportid     = {DKFZ-2024-01678},
      pages        = {709 - 714},
      year         = {2024},
      abstract     = {This review article discusses the currently available
                      evidence on the importance of biological and social sex in
                      pancreatic cancer in the context of the operative,
                      perioperative and multimodal treatment. In pancreatic cancer
                      there are gender differences with respect to the incidence,
                      treatment response and prognosis. Sex significantly
                      influences both innate and adaptive immune responses,
                      thereby affecting treatment response and survival rates.
                      Women are less likely to receive systemic treatment and tend
                      to wait longer for surgery but have better perioperative
                      outcomes after pancreatic resection. Overall, female
                      pancreatic cancer patients seem to have longer survival
                      under treatment; however, they report a subjectively lower
                      quality of life and higher disease burden.},
      subtyp        = {Review Article},
      keywords     = {Gender medicine (Other) / Immune response (Other) /
                      Pancreatic surgery (Other) / Precision medicine (Other) /
                      Treatment response (Other)},
      cin          = {D196},
      ddc          = {610},
      cid          = {I:(DE-He78)D196-20160331},
      pnm          = {314 - Immunologie und Krebs (POF4-314)},
      pid          = {G:(DE-HGF)POF4-314},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:39145868},
      doi          = {10.1007/s00104-024-02150-6},
      url          = {https://inrepo02.dkfz.de/record/292327},
}