000296203 001__ 296203
000296203 005__ 20251126134225.0
000296203 0247_ $$2doi$$a10.1158/2159-8290.CD-24-0194
000296203 0247_ $$2pmid$$apmid:39801234
000296203 0247_ $$2ISSN$$a2159-8274
000296203 0247_ $$2ISSN$$a2159-8290
000296203 0247_ $$2altmetric$$aaltmetric:172977105
000296203 037__ $$aDKFZ-2025-00116
000296203 041__ $$aEnglish
000296203 082__ $$a610
000296203 1001_ $$0P:(DE-He78)cc84982886796806e5def16a9fa227a1$$aVenkataramani, Varun$$b0$$eFirst author
000296203 245__ $$aCancer Neuroscience of Brain Tumors: From Multicellular Networks to Neuroscience-Instructed Cancer Therapies.
000296203 260__ $$aPhiladelphia, Pa.$$b[Verlag nicht ermittelbar]$$c2025
000296203 3367_ $$2DRIVER$$aarticle
000296203 3367_ $$2DataCite$$aOutput Types/Journal article
000296203 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1736779614_26799$$xReview Article
000296203 3367_ $$2BibTeX$$aARTICLE
000296203 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000296203 3367_ $$00$$2EndNote$$aJournal Article
000296203 500__ $$aDKFZ-ZMBH Alliance / #EA:B320#LA:B320#
000296203 520__ $$aDeepening our understanding of neuro-cancer interactions can innovate brain tumor treatment. This mini review unfolds the most relevant and recent insights into the neural mechanisms contributing to brain tumor initiation, progression, and resistance, including synaptic connections between neurons and cancer cells, paracrine neuro-cancer signaling, and cancer cells' intrinsic neural properties. We explain the basic and clinical-translational relevance of these findings, identify unresolved questions and particularly interesting future research avenues, such as central nervous system neuro-immunooncology, and discuss the potential transferability to extracranial cancers. Lastly, we conceptualize ways toward clinical trials and develop a roadmap toward neuroscience-instructed brain tumor therapies. Significance: Neural influences on brain tumors drive their growth and invasion. Herein, we develop a roadmap to use these fundamentally new insights into brain tumor biology for improved outcomes.
000296203 536__ $$0G:(DE-HGF)POF4-312$$a312 - Funktionelle und strukturelle Genomforschung (POF4-312)$$cPOF4-312$$fPOF IV$$x0
000296203 588__ $$aDataset connected to CrossRef, PubMed, , Journals: inrepo02.dkfz.de
000296203 650_2 $$2MeSH$$aHumans
000296203 650_2 $$2MeSH$$aBrain Neoplasms: pathology
000296203 650_2 $$2MeSH$$aAnimals
000296203 650_2 $$2MeSH$$aNeurosciences
000296203 7001_ $$0P:(DE-He78)c8cbb0d807975648e6ff0508697b0fbc$$aYang, Yvonne$$b1$$udkfz
000296203 7001_ $$00000-0003-2065-6464$$aIlle, Sebastian$$b2
000296203 7001_ $$00000-0002-1083-8232$$aSuchorska, Bogdana$$b3
000296203 7001_ $$0P:(DE-He78)1eee9e84c0f8c90a97fe40b6e8252a23$$aLoges, Sonja$$b4$$udkfz
000296203 7001_ $$00000-0002-7339-7569$$aTost, Heike$$b5
000296203 7001_ $$0P:(DE-He78)a1f4b408b9155beb2a8f7cba4d04fe88$$aSahm, Felix$$b6$$udkfz
000296203 7001_ $$0P:(DE-He78)f746aa965c4e1af518b016de3aaff5d9$$aPfister, Stefan$$b7$$udkfz
000296203 7001_ $$0P:(DE-He78)732f4fbcddb0042251aa759a2e74d3b2$$aTrumpp, Andreas$$b8$$udkfz
000296203 7001_ $$00000-0003-4050-1531$$aKrieg, Sandro M$$b9
000296203 7001_ $$00000-0003-1896-9031$$aKuner, Thomas$$b10
000296203 7001_ $$0P:(DE-He78)92e9783ca7025f36ce14e12cd348d2ee$$aWick, Wolfgang$$b11$$udkfz
000296203 7001_ $$0P:(DE-He78)6c294453ee36ad59deddc5494fa6aa4b$$aWinkler, Frank$$b12$$eLast author$$udkfz
000296203 773__ $$0PERI:(DE-600)2607892-2$$a10.1158/2159-8290.CD-24-0194$$gVol. 15, no. 1, p. 39 - 51$$n1$$p39 - 51$$tCancer discovery$$v15$$x2159-8274$$y2025
000296203 8564_ $$uhttps://inrepo02.dkfz.de/record/296203/files/cd-24-0194.pdf
000296203 8564_ $$uhttps://inrepo02.dkfz.de/record/296203/files/cd-24-0194.pdf?subformat=pdfa$$xpdfa
000296203 909CO $$ooai:inrepo02.dkfz.de:296203$$pVDB
000296203 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)cc84982886796806e5def16a9fa227a1$$aDeutsches Krebsforschungszentrum$$b0$$kDKFZ
000296203 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)c8cbb0d807975648e6ff0508697b0fbc$$aDeutsches Krebsforschungszentrum$$b1$$kDKFZ
000296203 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)1eee9e84c0f8c90a97fe40b6e8252a23$$aDeutsches Krebsforschungszentrum$$b4$$kDKFZ
000296203 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)a1f4b408b9155beb2a8f7cba4d04fe88$$aDeutsches Krebsforschungszentrum$$b6$$kDKFZ
000296203 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)f746aa965c4e1af518b016de3aaff5d9$$aDeutsches Krebsforschungszentrum$$b7$$kDKFZ
000296203 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)732f4fbcddb0042251aa759a2e74d3b2$$aDeutsches Krebsforschungszentrum$$b8$$kDKFZ
000296203 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)92e9783ca7025f36ce14e12cd348d2ee$$aDeutsches Krebsforschungszentrum$$b11$$kDKFZ
000296203 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)6c294453ee36ad59deddc5494fa6aa4b$$aDeutsches Krebsforschungszentrum$$b12$$kDKFZ
000296203 9131_ $$0G:(DE-HGF)POF4-312$$1G:(DE-HGF)POF4-310$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vFunktionelle und strukturelle Genomforschung$$x0
000296203 9141_ $$y2025
000296203 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2023-08-28
000296203 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2023-08-28
000296203 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2023-08-28
000296203 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2023-08-28
000296203 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2023-08-28
000296203 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2023-08-28
000296203 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2023-08-28
000296203 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2023-08-28
000296203 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bCANCER DISCOV : 2022$$d2023-08-28
000296203 915__ $$0StatID:(DE-HGF)9925$$2StatID$$aIF >= 25$$bCANCER DISCOV : 2022$$d2023-08-28
000296203 9202_ $$0I:(DE-He78)B320-20160331$$kB320$$lKKE Neuroonkologie$$x0
000296203 9201_ $$0I:(DE-He78)B320-20160331$$kB320$$lKKE Neuroonkologie$$x0
000296203 9201_ $$0I:(DE-He78)HD01-20160331$$kHD01$$lDKTK HD zentral$$x1
000296203 9201_ $$0I:(DE-He78)A420-20160331$$kA420$$lPersonalisierte Medizinische Onkologie$$x2
000296203 9201_ $$0I:(DE-He78)B300-20160331$$kB300$$lKKE Neuropathologie$$x3
000296203 9201_ $$0I:(DE-He78)B062-20160331$$kB062$$lB062 Pädiatrische Neuroonkologie$$x4
000296203 9201_ $$0I:(DE-He78)A010-20160331$$kA010$$lA010 Stammzellen und Krebs$$x5
000296203 9200_ $$0I:(DE-He78)B320-20160331$$kB320$$lKKE Neuroonkologie$$x0
000296203 980__ $$ajournal
000296203 980__ $$aVDB
000296203 980__ $$aI:(DE-He78)B320-20160331
000296203 980__ $$aI:(DE-He78)HD01-20160331
000296203 980__ $$aI:(DE-He78)A420-20160331
000296203 980__ $$aI:(DE-He78)B300-20160331
000296203 980__ $$aI:(DE-He78)B062-20160331
000296203 980__ $$aI:(DE-He78)A010-20160331
000296203 980__ $$aUNRESTRICTED