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@ARTICLE{Mokry:298578,
      author       = {T. Mokry$^*$ and J. Pantke and H.-U. Kauczor and F. B. Laun
                      and H.-P. Schlemmer$^*$ and T. A. Kuder$^*$ and S.
                      Bickelhaupt},
      title        = {{I}nfluence of field strength on quantitative parameters
                      and feature stability in the assessment of the ovaries using
                      1.5-{T} and 3-{T} {MRI}.},
      journal      = {Acta radiologica},
      volume       = {66},
      number       = {5},
      issn         = {0567-8056},
      address      = {London},
      publisher    = {Sage},
      reportid     = {DKFZ-2025-00295},
      pages        = {512-520},
      year         = {2025},
      note         = {2025 May;66(5):512-520},
      abstract     = {Little is known of the influence of scanner field strength
                      on quantitative diffusivity variables, especially kurtosis
                      in healthy ovaries.To evaluate the influence of scanner
                      field strength on quantitative diffusion variables in pelvic
                      MRI of the ovaries.This prospective, single-centre study
                      consisted of repeated 1.5-T and 3-T examinations in 30
                      female volunteers (mean age=27.9 years, age range=20.3-45.2
                      years) from July 2017 to September 2019. Multi b-value DWI
                      0, 50, 100, 800, 1500, 2000 s/mm2 was acquired over three
                      timepoints during the menstrual cycle. Ovaries were
                      segmented at b = 1500 s/mm2. Median apparent diffusion
                      coefficient (ADC) and advanced kurtosis parameters Dapp and
                      Kapp were calculated. Statistical analysis was performed
                      with the variations of diffusivity variables being compared
                      between 1.5-T and 3-T MRI using a Mann-Whitney rank-sum
                      test.Median ADC and Dapp (µm²/ms) did not statistically
                      differ. Median ADC were 1.509 (range=1.371-1.610), 1.619
                      (range=1.463-1.747), and 1.511 (range=1.423-1.639) at 1.5 T;
                      1.542 (range=1.428-1.682), 1.658 (range=1.510-1.806), and
                      1.572 (range=1.455-1.709) at 3 T (P = 0.14, 0.19, and 0.07),
                      whereas median Dapp were 2.024 (range=1.913-2.152), 2.192
                      (range=2.010-2.327), and 2.045 (range=1.958-2.170) at 1.5 T;
                      2.013 (range=1.952-2.188), 2.179 (range=2.018-2.327), and
                      2.082 (range=1.959-2.194) at 3 T (P = 0.77, 0.99, and 0.34)
                      for timepoints 1, 2, and 3, respectively. Statistical
                      comparison of Kapp revealed significant differences for all
                      timepoints: 0.629 (range=0.595-0.652), 0.604
                      (range=0.574-0.651), and 0.622 (range=0.581-0.664) at 1.5 T;
                      0.601 (range=0.563-0.626), 0.567 (range=0.526-0.633), and
                      0.599 (range=0.541-0.650) at 3 T (P < 0.001, 0.005, and
                      0.03).Diffusivity mapping in the ovaries provides similar
                      absolute median diffusion values, but statistically
                      significant differences in absolute kurtosis values between
                      1.5 T and 3 T.},
      keywords     = {Genital (Other) / adults (Other) / magnetic resonance
                      diffusion/perfusion (Other) / ovaries (Other) / reproductive
                      (Other)},
      cin          = {E010 / E020},
      ddc          = {610},
      cid          = {I:(DE-He78)E010-20160331 / I:(DE-He78)E020-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:39905712},
      doi          = {10.1177/02841851241313021},
      url          = {https://inrepo02.dkfz.de/record/298578},
}