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@ARTICLE{VidalVzquez:298613,
      author       = {N. Vidal-Vázquez and I. Hernández-Núñez and P.
                      Carballo-Pacoret and S. Salisbury and P. R. Villamayor and
                      F. Hervas-Sotomayor and X. Yuan and F. Lamanna and C.
                      Schneider and J. Schmidt$^*$ and S. Mazan and H. Kaessmann
                      and F. Adrio and D. Robledo and A. Barreiro-Iglesias and E.
                      Candal},
      title        = {{A} single-nucleus {RNA} sequencing atlas of the postnatal
                      retina of the shark {S}cyliorhinus canicula.},
      journal      = {Scientific data},
      volume       = {12},
      number       = {1},
      issn         = {2052-4436},
      address      = {London},
      publisher    = {Nature Publ. Group},
      reportid     = {DKFZ-2025-00313},
      pages        = {228},
      year         = {2025},
      note         = {DKFZ-ZMBH Alliance},
      abstract     = {The retina, whose basic cellular structure is highly
                      conserved across vertebrates, constitutes an accessible
                      system for studying the central nervous system. In recent
                      years, single-cell RNA sequencing studies have uncovered
                      cellular diversity in the retina of a variety of species,
                      providing new insights on retinal evolution and development.
                      However, similar data in cartilaginous fishes, the sister
                      group to all other extant jawed vertebrates, are still
                      lacking. Here, we present a single-nucleus RNA sequencing
                      atlas of the postnatal retina of the catshark Scyliorhinus
                      canicula, consisting of the expression profiles for 17,438
                      individual cells from three female, juvenile catshark
                      specimens. Unsupervised clustering revealed 22 distinct cell
                      types comprising all major retinal cell classes, as well as
                      retinal progenitor cells (whose presence reflects the
                      persistence of proliferative activity in postnatal stages in
                      sharks) and oligodendrocytes. Thus, our dataset serves as a
                      foundation for further studies on the development and
                      function of the catshark retina. Moreover, integration of
                      our atlas with data from other species will allow for a
                      better understanding of vertebrate retinal evolution.},
      keywords     = {Animals / Sharks: genetics / Retina: metabolism / Retina:
                      cytology / Female / Sequence Analysis, RNA / Single-Cell
                      Analysis},
      cin          = {A011},
      ddc          = {500},
      cid          = {I:(DE-He78)A011-20160331},
      pnm          = {311 - Zellbiologie und Tumorbiologie (POF4-311)},
      pid          = {G:(DE-HGF)POF4-311},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:39920165},
      pmc          = {pmc:PMC11806052},
      doi          = {10.1038/s41597-025-04547-2},
      url          = {https://inrepo02.dkfz.de/record/298613},
}