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024 7 _ |a 10.1016/j.jvir.2025.02.028
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024 7 _ |a 1051-0443
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024 7 _ |a 1535-7732
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037 _ _ |a DKFZ-2025-00490
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Tefera, Jonathan
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245 _ _ |a Portal and Hepatic Vein Embolization vs Portal Venous Embolization Alone in Cirrhotic and Non-cirrhotic Swine: A Pilot Study.
260 _ _ |a Amsterdam [u.a.]
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500 _ _ |a Volume 36, Issue 6, June 2025, Pages 1042-1050.e2
520 _ _ |a To evaluate the effectiveness of PVE and HVE compared to PVE in cirrhotic and non-cirrhotic swine.Sixteen Yorkshire pigs were included in this study. In the cirrhotic group (n = 8) and non-cirrhotic group (n = 8), subjects underwent embolization according to established protocols. CT scans were acquired before and at two- and four-week intervals following the embolization. Liver volumes were segmented in the portal venous phase. Student's t-test with a significance level at p<0.05 was used.Across all swine, the FLR was significantly larger after PVE + HVE to PVE at two weeks (24.12% [95% CI: 15.36%, 32.88%] vs. 12.75% [95% CI: 7.43%, 18.07%], p = 0.021) and four weeks (23.23% [95% CI: 15.79%, 33.47%] vs. 15.08% [95% CI: 9.98%, 20.87%], p = 0.043) post-embolization. In the cirrhotic group, the FLR increase was greater following PVE + HVE compared to PVE at two weeks (20.85% [95% CI: 14.40%, 27.30%] vs. 8.66% [95% CI: 6.47%, 10.86%], p = 0.0089) and four weeks (19.27% [95% CI: 17.87%, 20.67%] vs. 13.33% [95% CI: 9.23%, 13.33%], p = 0.0003) post-embolization.PVE + HVE resulted in greater FLR hypertrophy than PVE alone indicating that cirrhotic livers may benefit from the addition of HVE.
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700 1 _ |a Kuhn, Tom N
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700 1 _ |a Matuschewski, Nickolai J
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700 1 _ |a Meister, Ellen
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700 1 _ |a Nguyenová, Jana
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700 1 _ |a Kao, Tabea
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700 1 _ |a Mutonga, Martin
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700 1 _ |a Bitar, Ryan
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700 1 _ |a Kahl, Vinzent
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700 1 _ |a Zhang, Xuchen
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700 1 _ |a Shewarega, Annabella
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700 1 _ |a Chapiro, Julius
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700 1 _ |a Madoff, David C
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773 _ _ |a 10.1016/j.jvir.2025.02.028
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910 1 _ |a Deutsches Krebsforschungszentrum
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