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@ARTICLE{SnchezAlarcn:299798,
      author       = {M. F. Sánchez Alarcón and S. Dietrich-Conzelmann and J.
                      P. Bassenge and J. Schulz-Menger and S. Schmitter$^*$ and C.
                      S. Aigner},
      title        = {{R}eproducibility of tailored and universal nonselective
                      excitation pulses at 7 {T} for human cardiac {MRI}: {A}
                      3-year and an interday study.},
      journal      = {Magnetic resonance in medicine},
      volume       = {94},
      number       = {2},
      issn         = {1522-2594},
      address      = {New York, NY [u.a.]},
      publisher    = {Wiley-Liss},
      reportid     = {DKFZ-2025-00553},
      pages        = {588-601},
      year         = {2025},
      note         = {2025 Aug;94(2):588-601},
      abstract     = {Ultrahigh-field (UHF; ≥7 T) MRI is challenging due to
                      spatially heterogeneous B1 + profiles. This longitudinal
                      study evaluates the reproducibility of three
                      parallel-transmission excitation strategies to enable UHF
                      cardiac MRI: vendor-supplied radiofrequency (RF) shim,
                      subject-tailored kT-points pulses (TPs), and universal
                      kT-points pulses (UPs).Six healthy subjects underwent 7 T
                      MRI scans performed by different MR operators using a
                      32-element parallel-transmission body array at four time
                      points over 3 years. A single UP was computed and applied to
                      all subjects. TPs were computed individually for each scan
                      and organized into four configurations. Each configuration
                      was applied to all scans from each subject to analyze
                      intrasubject variability. Reproducibility was assessed by
                      comparing the coefficient of variation (CV) of simulated
                      flip angles (FAs) within the heart volume across scan
                      sessions.TPs designed for a specific scan session yielded
                      lower CVs (2-fold reduction) than UP. Applying TPs to other
                      scan sessions of the same subject, however, resulted in
                      approximately $40\%$ higher CVs and lower FA uniformity
                      compared with the UP. On average, the UP consistently
                      achieved the most reproducible results across inter-year,
                      inter-day, and same-operator studies, with CVs of
                      approximately $12\%.Although$ TPs showed advantages when
                      tailored for a specific target volume, they struggled with
                      long-term consistency and required lengthy calibration. The
                      precomputed UP kT-points pulses proved to be the most
                      consistent across all scans acquired in the 3 years by
                      different operators, minimizing CV-data dispersion and
                      maintaining FA uniformity.},
      keywords     = {7 Tesla (Other) / cardiac MRI (Other) / parallel
                      transmission (Other) / universal pulse (Other)},
      cin          = {E020},
      ddc          = {610},
      cid          = {I:(DE-He78)E020-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40079582},
      doi          = {10.1002/mrm.30495},
      url          = {https://inrepo02.dkfz.de/record/299798},
}