Journal Article (Review Article)

DKFZ-2025-00854

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Early-onset colorectal cancer : When should we start with screening? [Darmkrebs bei jungen Erwachsenen : Wann sollte das Screening beginnen?]

Hoffmeister, M. (First author)DKFZ* ; Brenner, H. (Last author)DKFZ*

2025
Springer Medizin Verlag GmbH [Berlin]

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Please use a persistent id in citations: doi:10.1007/s00117-025-01453-x

Abstract: In recent years, the number of new cases of colorectal cancer in people under the age of 50 (early-onset colorectal cancer, EOCRC) has increased, and extension of colorectal cancer screening for younger age groups is currently being discussed.To discuss whether the age for population-wide colorectal cancer screening should be lowered?Extension of population-wide screening to younger age groups particularly to those under the age of 40 would be highly inefficient due to the low colorectal cancer incidence. Still, it could be considered for people at increased risk, including young adults with familial risk. Implementation of primary prevention measures would already be possible.More targeted risk-adapted prevention and screening strategies are needed to reverse the rising trend of EOCRC and to detect colorectal cancer more frequently at an early stage.

Keyword(s): Early detection of cancer ; Epidemiology ; Preventive care ; Prognosis ; Risk factors

Note: #EA:C070#LA:C070# / 2025 Jun;65(6):405-409 / M320

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Contributing Institute(s):

1. C070 Klinische Epidemiologie der Krebsfrüherkennung (C070)

Research Program(s):

1. 313 - Krebsrisikofaktoren und Prävention (POF4-313) (POF4-313)

Appears in the scientific report 2025

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Database coverage:
; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; DEAL Springer ; DEAL Springer ; Essential Science Indicators ; IF < 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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