TY  - JOUR
AU  - Scarpetta, Valentina
AU  - Ho, Kim Hoa
AU  - Trapp, Marleen
AU  - Patrizi, Annarita
TI  - Choroid plexus: Insights from distinct epithelial cellular components.
JO  - Current opinion in neurobiology
VL  - 93
SN  - 0959-4388
CY  - Philadelphia, Pa.
PB  - Current Biology
M1  - DKFZ-2025-00856
SP  - 103028
PY  - 2025
N1  - #EA:A320#LA:A320# / Schaller Research Group, German Cancer Research Center (DKFZ)
AB  - The choroid plexus (ChP) serves as a vital interface between blood and cerebrospinal fluid (CSF), playing a pivotal role in central nervous system (CNS) development and communication with the body. This review mainly summarizes how the ChP epithelial cells respond to physiological and pathological stimuli, emphasizing the role of distinct organelles and key molecular signaling pathways. Additionally, we discuss the roles of ChP cilia, an evolutionary conserved organelle whose function is still under investigation. Understanding these processes is essential for elucidating how ChP function modulates intrinsic and extrinsic stimuli, which are crucial for maintaining CNS and body homeostasis.
LB  - PUB:(DE-HGF)16
C6  - pmid:40267629
DO  - DOI:10.1016/j.conb.2025.103028
UR  - https://inrepo02.dkfz.de/record/300645
ER  -