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@ARTICLE{Lv:300826,
author = {W. Lv and Y. Zeng and C. Li and Y. Liang and H. Tao and Y.
Zhu and X. Sui and Y. Li and S. Jiang and Q. Gao and E.
Rodriguez-Fos and G. Prasad and Y. Wang and R. Zhou and Z.
Xu and X. Pan and L. Chen and X. Xiang and H. Teng and C.
Sun and T. Qin and W. Dong and Y. Li and X. Lan and X. Li
and L. Lin and L. Bolund and H. Yang and R. G. W. Verhaak
and B. M. Faltas and J. B. Hansen and S. Wu and P. S.
Mischel and A. G. Henssen$^*$ and V. Bafna and J. Luebeck
and B. Regenberg and Y. Luo and C. Lin and P. Han},
title = {{S}patial-{T}emporal {D}iversity of {E}xtrachromosomal
{DNA} {S}hapes {U}rothelial {C}arcinoma {E}volution and the
{T}umor {I}mmune {M}icroenvironment.},
journal = {Cancer discovery},
volume = {15},
number = {6},
issn = {2159-8274},
address = {Philadelphia, Pa.},
publisher = {[Verlag nicht ermittelbar]},
reportid = {DKFZ-2025-00940},
pages = {1225–1246},
year = {2025},
note = {Cancer Discov (2025) 15 (6): 1225–1246},
abstract = {Our comprehensive analysis of ecDNA in urothelial carcinoma
reveals its crucial role in driving the evolution and
heterogeneity of multifocal cancer, as well as its early
involvement in tumorigenesis. Moreover, this study sheds
light on immune evasion mechanisms associated with ecDNA and
offers valuable insights for developing targeted therapeutic
strategies.},
cin = {BE01},
ddc = {610},
cid = {I:(DE-He78)BE01-20160331},
pnm = {899 - ohne Topic (POF4-899)},
pid = {G:(DE-HGF)POF4-899},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:40331621},
doi = {10.1158/2159-8290.CD-24-1532},
url = {https://inrepo02.dkfz.de/record/300826},
}