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@ARTICLE{Zalevskaja:301313,
      author       = {K. Zalevskaja and K. Ojala and A. Petrov and S. Haupt and
                      L. Sunde and I. Bernstein and M. A. Jenkins and S. Aretz and
                      M. Nielsen and G. Capella and F. Balaguer and D. G. Evans
                      and J. Burn and E. Holinski-Feder and L. Bertario and B.
                      Bonanni and A. Lindblom and Z. Levi and F. Macrae and I.
                      Winship and J.-P. Plazzer and R. Sijmons and L. Laghi and A.
                      Della Valle and K. Heinimann and T. Dębniak and R. Fruscio
                      and F. Lopez-Koestner and K. Alvarez-Valenzuela and L. H.
                      Katz and I. Laish and E. Vainer and C. Vaccaro and D. M.
                      Carraro and K. Monahan and E. Half and A. Stakelum and D.
                      Winter and R. Kennelly and N. Gluck and H. Sheth and N.
                      Abu-Freha and M. Greenblatt and B. M. Rossi and M. Bohorquez
                      and G. M. Cavestro and L. S. Lino-Silva and K. Horisberger
                      and M. G. Tibiletti and I. do Nascimento and H. Thomas and
                      N. T. Rossi and L. A. da Silva and A. Zaránd and J.
                      Ruiz-Bañobre and V. Heuveline and L. J. Lindberg and I.
                      Gögenur and J. L. Hopper and A. K. Win and R. W. Haile and
                      N. Lindor and S. Gallinger and L. Le Marchand and P. A.
                      Newcomb and J. Figueiredo and D. D. Buchanan and S. N.
                      Thibodeau and M. von Knebel Doeberitz$^*$ and M. Loeffler
                      and N. Rahner and E. Schröck$^*$ and V. Steinke-Lange and
                      W. Schmiegel and D. Vangala and C. Perne and R. Hüneburg
                      and S. Redler$^*$ and R. Büttner and J. Weitz and M. Pineda
                      and N. Duenas and J. Brunet Vidal and L. Moreira and A.
                      Sánchez and J. Castillo-Iturra and E. Hovig and K. Green
                      and F. Lalloo and J. Hill and E. Crosbie and M. Mints and Y.
                      Goldberg and D. Tjandra and S. W. ten Broeke and R. Kariv
                      and G. Rosner and A. Jain and P. Shah and M. Shah and F.
                      Neffa and P. Esperon and W. Pavicic and G. T. Torrezan and
                      T. Bassaneze and C. A. Martin and K. Pylvänäinen and G.
                      Möslein and A. Lepistö and J.-P. Mecklin and L.
                      Renkonen-Sinisalo and J. R. Sampson and M. Dominguez
                      Valentin and P. Møller and T. T. Seppälä},
      title        = {{M}etachronous colorectal cancer risks after extended or
                      segmental resection in {MLH}1 , {MSH}2 , and {MSH}6 {L}ynch
                      syndrome: multicentre study from the {P}rospective {L}ynch
                      {S}yndrome {D}atabase},
      journal      = {The British journal of surgery},
      volume       = {112},
      number       = {4},
      issn         = {0263-1202},
      address      = {Oxford},
      publisher    = {Oxford University Press},
      reportid     = {DKFZ-2025-00985},
      pages        = {znaf061},
      year         = {2025},
      abstract     = {This first prospective observational study evaluates the
                      impact of extended versus segmental colorectal surgery on
                      the risk of metachronous colorectal cancer (CRC) in patients
                      with Lynch syndrome, analyzing data from the Prospective
                      Lynch Syndrome Database version 5. Extended resection
                      significantly reduced the risk of metachronous CRC in
                      $path_MLH1,$ $path_MSH2,$ and $path_MSH6$ carriers compared
                      to segmental resection.},
      cin          = {D470 / DD01},
      ddc          = {610},
      cid          = {I:(DE-He78)D470-20160331 / I:(DE-He78)DD01-20160331},
      pnm          = {314 - Immunologie und Krebs (POF4-314)},
      pid          = {G:(DE-HGF)POF4-314},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40231433},
      doi          = {10.1093/bjs/znaf061},
      url          = {https://inrepo02.dkfz.de/record/301313},
}