%0 Journal Article
%A Bulanov, Petr
%A Menshchikov, Petr
%A Grimm, Johannes
%A Lutz, Max
%A Orzada, Stephan
%A Boyd, Philip
%A Bachert, Peter
%A Ladd, Mark
%A Korzowski, Andreas
%A Schmitter, Sebastian
%T Human liver CEST imaging at 7 T: Impact of B 1 + shimming.
%J Magnetic resonance in medicine
%V 94
%N 4
%@ 1522-2594
%C New York, NY [u.a.]
%I Wiley-Liss
%M DKFZ-2025-01075
%P 1604-1615
%D 2025
%Z #EA:E020#LA:E020# / Volume 94, Issue 4 pp. 1604-1615
%X To explore the feasibility of CEST imaging in the human liver at 7 T with B 1 + 
%X <br clear="all" /><table border="0" width="100%"><tr><td>
%X <table align="center" cellspacing="0"  cellpadding="2"><tr><td nowrap="nowrap" align="center">
%X  B<sub>1</sub><sup>+</sup> </td></tr></table>
%X </td></tr></table>
%X 
%X  shimming.CEST MRI was performed on a 7 T whole-body scanner with a parallel transmission (pTx) system in five healthy volunteers. Static pTx ( B 1 + 
%X <br clear="all" /><table border="0" width="100%"><tr><td>
%X <table align="center" cellspacing="0"  cellpadding="2"><tr><td nowrap="nowrap" align="center">
%X  B<sub>1</sub><sup>+</sup> </td></tr></table>
%X </td></tr></table>
%X 
%X  shimming) was applied to locally maximize the B 1 + 
%X <br clear="all" /><table border="0" width="100%"><tr><td>
%X <table align="center" cellspacing="0"  cellpadding="2"><tr><td nowrap="nowrap" align="center">
%X  B<sub>1</sub><sup>+</sup> </td></tr></table>
%X </td></tr></table>
%X 
%X  magnitude per input power within a given region of interest (ROI) of approximately 30 mm diameter (ROIshim). Relaxation-compensated inverse magnetization transfer ratio (MTRRex) values were quantified for amide protons, guanidino protons, and relayed nuclear Overhauser effect signals based on five-pool Lorentzian fit analysis. MTRRex values were corrected for B1 inhomogeneities using an absolute, accurate MR fingerprinting-based B 1 + 
%X <br clear="all" /><table border="0" width="100%"><tr><td>
%X <table align="center" cellspacing="0"  cellpadding="2"><tr><td nowrap="nowrap" align="center">
%X  B<sub>1</sub><sup>+</sup> </td></tr></table>
%X </td></tr></table>
%X 
%X  mapping technique.Within the ROIshim, reliable MTRRex values could be calculated for an average of 85
%K 7 T (Other)
%K B1 correction (Other)
%K B1+                                                                                                                             B                                                        1                                                           +                                                                                                 $$ {B}_1^{+} $$                                    shimming (Other)
%K body CEST (Other)
%K liver CEST (Other)
%K pTx (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40411372
%R 10.1002/mrm.30557
%U https://inrepo02.dkfz.de/record/301567