TY  - JOUR
AU  - Bulanov, Petr
AU  - Menshchikov, Petr
AU  - Grimm, Johannes
AU  - Lutz, Max
AU  - Orzada, Stephan
AU  - Boyd, Philip
AU  - Bachert, Peter
AU  - Ladd, Mark
AU  - Korzowski, Andreas
AU  - Schmitter, Sebastian
TI  - Human liver CEST imaging at 7 T: Impact of B 1 + shimming.
JO  - Magnetic resonance in medicine
VL  - 94
IS  - 4
SN  - 1522-2594
CY  - New York, NY [u.a.]
PB  - Wiley-Liss
M1  - DKFZ-2025-01075
SP  - 1604-1615
PY  - 2025
N1  - #EA:E020#LA:E020# / Volume 94, Issue 4 pp. 1604-1615
AB  - To explore the feasibility of CEST imaging in the human liver at 7 T with B 1 + 
AB  - <br clear="all" /><table border="0" width="100%"><tr><td>
AB  - <table align="center" cellspacing="0"  cellpadding="2"><tr><td nowrap="nowrap" align="center">
AB  -  B<sub>1</sub><sup>+</sup> </td></tr></table>
AB  - </td></tr></table>
AB  - 
AB  -  shimming.CEST MRI was performed on a 7 T whole-body scanner with a parallel transmission (pTx) system in five healthy volunteers. Static pTx ( B 1 + 
AB  - <br clear="all" /><table border="0" width="100%"><tr><td>
AB  - <table align="center" cellspacing="0"  cellpadding="2"><tr><td nowrap="nowrap" align="center">
AB  -  B<sub>1</sub><sup>+</sup> </td></tr></table>
AB  - </td></tr></table>
AB  - 
AB  -  shimming) was applied to locally maximize the B 1 + 
AB  - <br clear="all" /><table border="0" width="100%"><tr><td>
AB  - <table align="center" cellspacing="0"  cellpadding="2"><tr><td nowrap="nowrap" align="center">
AB  -  B<sub>1</sub><sup>+</sup> </td></tr></table>
AB  - </td></tr></table>
AB  - 
AB  -  magnitude per input power within a given region of interest (ROI) of approximately 30 mm diameter (ROIshim). Relaxation-compensated inverse magnetization transfer ratio (MTRRex) values were quantified for amide protons, guanidino protons, and relayed nuclear Overhauser effect signals based on five-pool Lorentzian fit analysis. MTRRex values were corrected for B1 inhomogeneities using an absolute, accurate MR fingerprinting-based B 1 + 
AB  - <br clear="all" /><table border="0" width="100%"><tr><td>
AB  - <table align="center" cellspacing="0"  cellpadding="2"><tr><td nowrap="nowrap" align="center">
AB  -  B<sub>1</sub><sup>+</sup> </td></tr></table>
AB  - </td></tr></table>
AB  - 
AB  -  mapping technique.Within the ROIshim, reliable MTRRex values could be calculated for an average of 85
KW  - 7 T (Other)
KW  - B1 correction (Other)
KW  - B1+                                                                                                                             B                                                        1                                                           +                                                                                                 $$ {B}_1^{+} $$                                    shimming (Other)
KW  - body CEST (Other)
KW  - liver CEST (Other)
KW  - pTx (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40411372
DO  - DOI:10.1002/mrm.30557
UR  - https://inrepo02.dkfz.de/record/301567
ER  -