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@ARTICLE{Brenner:301914,
      author       = {H. Brenner$^*$ and D. Sergeev$^*$ and T. Heisser$^*$ and M.
                      Hoffmeister$^*$},
      title        = {{R}esearch {C}ommunication: {E}ffects of {S}creening
                      {C}olonoscopyon {C}olorectal {C}ancer {M}ortality: {L}essons
                      {F}rom {C}omparative{A}nalyses of {R}andomised {T}rials},
      journal      = {Alimentary pharmacology $\&$ therapeutics},
      volume       = {62},
      number       = {6},
      issn         = {0269-2813},
      address      = {Oxford},
      publisher    = {Blackwell Science},
      reportid     = {DKFZ-2025-01184},
      pages        = {656-659},
      year         = {2025},
      note         = {#EA:C070#LA:C070# / 2025 Sep;62(6):656-659},
      abstract     = {NordICC, the first randomised trial on long-term effects of
                      screening colonoscopy, failed to demonstrate a significant
                      reduction in colorectal cancer (CRC) mortality. We compared
                      reported 10-year CRC mortality results from NordICC with
                      those of NORCCAP, a similarly designed pragmatic
                      sigmoidoscopy trial. In NORCCAP, differences in CRC
                      mortality only began to emerge after 9.5 years of follow-up,
                      rapidly increased thereafter and were approximately 4-fold
                      as high after 12 years than after 10 years. Other
                      sigmoidoscopy trials yielded similar 11- to 12-year results.
                      Our analysis suggests that the apparent negative CRC
                      mortality results of NordICC primarily reflect insufficient
                      follow-up time.},
      keywords     = {colonoscopy (Other) / colorectal cancer (Other) / mortality
                      (Other) / screening (Other)},
      cin          = {C070 / HD01},
      ddc          = {610},
      cid          = {I:(DE-He78)C070-20160331 / I:(DE-He78)HD01-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40492318},
      doi          = {DOI:10.1111/apt.70231},
      url          = {https://inrepo02.dkfz.de/record/301914},
}