000302033 001__ 302033
000302033 005__ 20250622021242.0
000302033 0247_ $$2doi$$a10.1016/j.xpro.2025.103887
000302033 0247_ $$2pmid$$apmid:40516045
000302033 0247_ $$2altmetric$$aaltmetric:178216046
000302033 037__ $$aDKFZ-2025-01224
000302033 041__ $$aEnglish
000302033 082__ $$a600
000302033 1001_ $$aAtatri, Sura$$b0
000302033 245__ $$aProtocol for sub-mucosal orthotopic injection of organoids into murine colon to study tumor growth and metastasis.
000302033 260__ $$aCambridge, MA$$bCell Press$$c2025
000302033 3367_ $$2DRIVER$$aarticle
000302033 3367_ $$2DataCite$$aOutput Types/Journal article
000302033 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1750141025_24495
000302033 3367_ $$2BibTeX$$aARTICLE
000302033 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000302033 3367_ $$00$$2EndNote$$aJournal Article
000302033 520__ $$aOrthotopic mouse models of colorectal cancer (CRC) better recapitulate the physiological processes of tumor development and metastatic dissemination. Here, we provide a protocol for colonoscopy-guided transplantation of organoids into the murine colon. We describe the steps for preparing mouse organoids, equipment, and mice for injections, as well as performing colonoscopy-guided mucosal injections and providing subsequent care. This model can be used to investigate various experimental setups, including survival, metastatic potential, and the effects of treatments. For complete details on the use and execution of this protocol, please refer to Felchle et al.1.
000302033 536__ $$0G:(DE-HGF)POF4-899$$a899 - ohne Topic (POF4-899)$$cPOF4-899$$fPOF IV$$x0
000302033 588__ $$aDataset connected to CrossRef, PubMed, , Journals: inrepo02.dkfz.de
000302033 650_7 $$2Other$$aCancer
000302033 650_7 $$2Other$$aHealth Sciences
000302033 650_7 $$2Other$$aModel Organisms
000302033 650_7 $$2Other$$aOrganoids
000302033 7001_ $$aMeyers, Marianne$$b1
000302033 7001_ $$aKlein, Eliane$$b2
000302033 7001_ $$aBrunner, Valentina$$b3
000302033 7001_ $$0P:(DE-He78)aebebbcb6f81435b697f2349293b2984$$aTschurtschenthaler, Markus$$b4$$udkfz
000302033 7001_ $$aLetellier, Elisabeth$$b5
000302033 773__ $$0PERI:(DE-600)3053335-1$$a10.1016/j.xpro.2025.103887$$gVol. 6, no. 2, p. 103887 -$$n2$$p103887$$tSTAR Protocols$$v6$$x2666-1667$$y2025
000302033 909CO $$ooai:inrepo02.dkfz.de:302033$$pVDB
000302033 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)aebebbcb6f81435b697f2349293b2984$$aDeutsches Krebsforschungszentrum$$b4$$kDKFZ
000302033 9131_ $$0G:(DE-HGF)POF4-899$$1G:(DE-HGF)POF4-890$$2G:(DE-HGF)POF4-800$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bProgrammungebundene Forschung$$lohne Programm$$vohne Topic$$x0
000302033 9141_ $$y2025
000302033 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2024-12-31
000302033 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2024-12-31
000302033 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2023-04-12T14:51:27Z
000302033 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2023-04-12T14:51:27Z
000302033 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bDOAJ : Anonymous peer review$$d2023-04-12T14:51:27Z
000302033 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2024-12-31
000302033 915__ $$0StatID:(DE-HGF)0112$$2StatID$$aWoS$$bEmerging Sources Citation Index$$d2024-12-31
000302033 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2024-12-31
000302033 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2024-12-31
000302033 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2024-12-31
000302033 915__ $$0StatID:(DE-HGF)0561$$2StatID$$aArticle Processing Charges$$d2024-12-31
000302033 915__ $$0StatID:(DE-HGF)0700$$2StatID$$aFees$$d2024-12-31
000302033 9201_ $$0I:(DE-He78)MU01-20160331$$kMU01$$lDKTK Koordinierungsstelle München$$x0
000302033 980__ $$ajournal
000302033 980__ $$aVDB
000302033 980__ $$aI:(DE-He78)MU01-20160331
000302033 980__ $$aUNRESTRICTED