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| Home > Publications database > Lower rate of pancreatobiliary complications after sludge and microlithiasis pancreatitis compared to gallstone pancreatitis. > print |
| 001 | 302790 | ||
| 005 | 20250829103033.0 | ||
| 024 | 7 | _ | |a 10.1016/j.dld.2025.06.005 |2 doi |
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| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Sirtl, Simon |b 0 |
| 245 | _ | _ | |a Lower rate of pancreatobiliary complications after sludge and microlithiasis pancreatitis compared to gallstone pancreatitis. |
| 260 | _ | _ | |a [Erscheinungsort nicht ermittelbar] |c 2025 |b Saunders |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1756456189_12781 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 500 | _ | _ | |a Volume 57, Issue 9, September 2025, Pages 1810-1818 |
| 520 | _ | _ | |a Cholecystectomy is recommended to prevent recurrence of biliary pancreatitis, but supporting evidence is limited for sludge- and microlithiasis-induced acute pancreatitis (AP). This study aimed to compare relapse patterns and risk factors between patients with sludge/microlithiasis-induced AP and gallstone-induced AP.This analysis included 789 patients from the international, multicenter Relapstone cohort (Spain: 16 centers; Mexico: 2 centers), hospitalized between January 2018 and April 2020 with first-time biliary AP and no cholecystectomy during admission. Patients with sludge/microlithiasis-induced AP (n = 274) were compared to those with gallstone-induced AP (n = 515) regarding pancreatobiliary complications. Multivariate analysis was used to assess relapse risk factors.Pancreatobiliary complications occurred in 41.7 % of the gallstone cohort versus 32.1 % in the sludge/microlithiasis cohort (p = 0.01). Correspondingly, the gallstone AP cohort showed a significantly lower complication-free survival rate (log-rank p = 0.0022; median follow-up: 6.1 vs. 8.1 months). In multivariate analysis, older age in the gallstone group was significantly associated with lower relapse risk (HR = 0.54, 95 % CI: 0.39-0.74).This multicenter study reveals distinct differences in relapse risk between gallstone- and sludge/microlithiasis-induced AP, with gallstone AP showing a higher rate of complications in the absence of cholecystectomy. |
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| 650 | _ | 7 | |a Acute pancreatitis |2 Other |
| 650 | _ | 7 | |a Biliary pancreatitis |2 Other |
| 650 | _ | 7 | |a Gallstones |2 Other |
| 650 | _ | 7 | |a Microlithiasis |2 Other |
| 650 | _ | 7 | |a Sludge |2 Other |
| 700 | 1 | _ | |a Teodorescu, Bianca |0 P:(DE-HGF)0 |b 1 |
| 700 | 1 | _ | |a Gilberg, Leonard |b 2 |
| 700 | 1 | _ | |a Schäfer, Arlett |b 3 |
| 700 | 1 | _ | |a Beyer, Georg |b 4 |
| 700 | 1 | _ | |a Arnau, Anna |b 5 |
| 700 | 1 | _ | |a López-Guillén, Pablo |b 6 |
| 700 | 1 | _ | |a Martínez-Domínguez, Samuel J |b 7 |
| 700 | 1 | _ | |a Baroja, Daniel Abad |b 8 |
| 700 | 1 | _ | |a Oyón, Daniel |b 9 |
| 700 | 1 | _ | |a Ruiz-Belmonte, Lara M |b 10 |
| 700 | 1 | _ | |a Tejedor-Tejada, Javier |b 11 |
| 700 | 1 | _ | |a Zapater, Raul |b 12 |
| 700 | 1 | _ | |a Martín-Vicente, Noelia |b 13 |
| 700 | 1 | _ | |a Fernández-Esparcia, Pedro José |b 14 |
| 700 | 1 | _ | |a Gomara, Ana Belén Julián |b 15 |
| 700 | 1 | _ | |a Lozano, Violeta Sastre |b 16 |
| 700 | 1 | _ | |a García, Juan José Manzanares |b 17 |
| 700 | 1 | _ | |a Martín-Falquina, Irene Chivato |b 18 |
| 700 | 1 | _ | |a Pascual, Laura Andrés |b 19 |
| 700 | 1 | _ | |a Monclus, Nuria Torres |b 20 |
| 700 | 1 | _ | |a Velasco, Natividad Zaragoza |b 21 |
| 700 | 1 | _ | |a Rojo, Eukene |b 22 |
| 700 | 1 | _ | |a Lapeña-Muñoz, Berta |b 23 |
| 700 | 1 | _ | |a Flores, Virginia |b 24 |
| 700 | 1 | _ | |a Gómez, Arantxa Díaz |b 25 |
| 700 | 1 | _ | |a Cañamares-Orbís, Pablo |b 26 |
| 700 | 1 | _ | |a Abizanda, Isabel Vinzo |b 27 |
| 700 | 1 | _ | |a Carrasco, Natalia Marcos |b 28 |
| 700 | 1 | _ | |a Grau, Laura Pardo |b 29 |
| 700 | 1 | _ | |a García-Rayado, Guillermo |b 30 |
| 700 | 1 | _ | |a Bocos, Judith Millastre |b 31 |
| 700 | 1 | _ | |a de Paredes, Ana Garcia Garcia |b 32 |
| 700 | 1 | _ | |a Lorenzo, María Vaamonde |b 33 |
| 700 | 1 | _ | |a Arostegi, Arantzazu Izagirre |b 34 |
| 700 | 1 | _ | |a Lozada-Hernández, Edgard Efrén |b 35 |
| 700 | 1 | _ | |a Velasco, José Antonio Velarde-Ruiz |b 36 |
| 700 | 1 | _ | |a Żorniak, Michal |b 37 |
| 700 | 1 | _ | |a de-Madaria, Enrique |b 38 |
| 700 | 1 | _ | |a Mayerle, Julia |b 39 |
| 700 | 1 | _ | |a Velamazán, Raúl |b 40 |
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