%0 Journal Article
%A Glowa, Christin
%A Saager, Maria
%A Hintz, Lisa
%A Euler-Lange, Rosemarie
%A Peschke, Peter
%A Brons, Stephan
%A Hilt, Kaya
%A Friedrich, Thomas
%A Scholz, Michael
%A Liew, Hans
%A Mairani, Andrea
%A Karger, Christian
%T Variable Relative Biological Effectiveness of Protons in the Rat Spinal Cord: Measurements and Comparison With Model Calculations.
%J Advances in radiation oncology
%V 10
%N 8
%@ 2452-1094
%C Amsterdam
%I Elsevier
%M DKFZ-2025-01440
%P 101809
%D 2025
%Z #EA:E040#LA:E040#
%X To determine the relative biological effectiveness (RBE) in the rat spinal cord after 6 fractions of protons as a function of linear energy transfer (LET) and dose.The rat spinal cord was irradiated at 4 different positions of a 6 cm spread-out Bragg peak using 6 fractions of protons (LET: 1.4, 2.7, 3.9, and 5.5 keV/µm). Dose-response curves were established for the endpoint paresis grade 2, and the RBE was calculated based on the dose at 50
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40678668
%2 pmc:PMC12269397
%R 10.1016/j.adro.2025.101809
%U https://inrepo02.dkfz.de/record/302993