TY - JOUR
AU - Glowa, Christin
AU - Saager, Maria
AU - Hintz, Lisa
AU - Euler-Lange, Rosemarie
AU - Peschke, Peter
AU - Brons, Stephan
AU - Hilt, Kaya
AU - Friedrich, Thomas
AU - Scholz, Michael
AU - Liew, Hans
AU - Mairani, Andrea
AU - Karger, Christian
TI - Variable Relative Biological Effectiveness of Protons in the Rat Spinal Cord: Measurements and Comparison With Model Calculations.
JO - Advances in radiation oncology
VL - 10
IS - 8
SN - 2452-1094
CY - Amsterdam
PB - Elsevier
M1 - DKFZ-2025-01440
SP - 101809
PY - 2025
N1 - #EA:E040#LA:E040#
AB - To determine the relative biological effectiveness (RBE) in the rat spinal cord after 6 fractions of protons as a function of linear energy transfer (LET) and dose.The rat spinal cord was irradiated at 4 different positions of a 6 cm spread-out Bragg peak using 6 fractions of protons (LET: 1.4, 2.7, 3.9, and 5.5 keV/µm). Dose-response curves were established for the endpoint paresis grade 2, and the RBE was calculated based on the dose at 50
LB - PUB:(DE-HGF)16
C6 - pmid:40678668
C2 - pmc:PMC12269397
DO - DOI:10.1016/j.adro.2025.101809
UR - https://inrepo02.dkfz.de/record/302993
ER -