%0 Journal Article %A Katzke, Verena %A Dutta, Srimanti %A Rasokat, Anna %A Archibugi, Livia %A Capurso, Gabriele %A Peduzzi, Giulia %A Gentiluomo, Manuel %A Canzian, Federico %A Eriksen, Anne Kirstine %A Tjønneland, Anne %A Dahm, Christina C %A Truong, Therese %A Canonico, Marianne %A Laouali, Nasser %A Schulze, Matthias B %A Tumino, Rosario %A Masala, Giovanna %A Agnoli, Claudia %A Dansero, Lucia %A Panico, Salvatore %A Crous-Bou, Marta %A Molina-Montes, Esther %A Dorronsoro, Ane %A Chirlaque, María-Dolores %A Guevara, Marcela %A Butt, Salma Tunå %A Sund, Malin %A Christakoudi, Sofia %A Aglago, Elom K %A Weiderpass, Elisabete %A Gunter, Marc %A Campa, Daniele %A Kaaks, Rudolf %T Sex Disparities and Female Reproductive and Hormonal Factors Associated with Risk of Pancreatic Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) Cohort. %J Cancers %V 17 %N 14 %@ 2072-6694 %C Basel %I MDPI %M DKFZ-2025-01580 %P 2275 %D 2025 %Z #EA:C020#LA:C020# %X Background/Objectives: Worldwide, men experience a higher incidence of pancreatic cancer (PC) than women. Methods: To increase understanding of the underlying reasons for this sex-related difference, we analysed general and sex-related risk factors for PC in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort (women/men No. = 293,682/136,728; 717/577 PC-cases). Results: Cox proportional hazards models showed a 1.31-fold higher risk of developing PC for men compared to women (HR, 95 %K EPIC study (Other) %K hormonal factors (Other) %K pancreatic cancer (Other) %K reproductive factors (Other) %K sex differences (Other) %K women (Other) %F PUB:(DE-HGF)16 %9 Journal Article %$ pmid:40723159 %R 10.3390/cancers17142275 %U https://inrepo02.dkfz.de/record/303229