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082 _ _ |a 610
100 1 _ |a Endrös, Lukas
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245 _ _ |a Focal iron sparing mimicking liver lesion in post-transfusion iron overload: A case report.
260 _ _ |a Seattle, Wash.
|c 2025
|b University of Washington
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520 _ _ |a Iron sparing, a rare imaging phenomenon in the context of hepatic iron overload, can mimic true liver lesions and pose significant diagnostic challenges-especially in oncologic patients with a history of frequent blood transfusions. We present the case of a 68-year-old woman with metastatic breast cancer and transfusion-dependent anemia who developed hepatic iron overload following multiple red blood cell transfusions. MRI showed a hyperintense lesion in segment 4b on a fat-suppressed Dixon sequence, raising initial concern for pathology. T2* mapping and chemical shift imaging revealed hepatic iron overload with relative sparing in segment 4, characterized by a marked signal drop on in-phase imaging and reduced T2* relaxation time in the surrounding liver parenchyma; the spared region itself showed a comparatively longer T2* time, consistent with focal iron sparing rather than a true lesion. Additionally, an aberrant right gastric vein supplying this region suggested altered perfusion as a possible underlying mechanism. This case underscores the importance of identifying focal iron sparing to prevent misdiagnosis and avoid unwarranted interventions.
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650 _ 7 |a Case report
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650 _ 7 |a Focal iron sparing
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650 _ 7 |a Iron overload
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650 _ 7 |a Liver MRI
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650 _ 7 |a MRI pitfalls
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650 _ 7 |a Pseudolesion
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700 1 _ |a Hesse, Felix
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700 1 _ |a Braren, Rickmer
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700 1 _ |a Steinhelfer, Lisa
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773 _ _ |a 10.1016/j.radcr.2025.07.024
|g Vol. 20, no. 11, p. 5478 - 5483
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|t Radiology case reports
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|y 2025
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